Pharmacist Led Intervention in the Management of Anemia Among Pregnant woman-a Randomized Controlled Trial
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Change in hemoglobin concentration
研究概览
简要总结
Anemia is a major public health problem among pregnant women, particularly in low- and middle-income countries. It is characterized by a reduction in hemoglobin concentration or the oxygen-carrying capacity of the blood, which may be insufficient to meet the physiological needs of the body. Maternal anemia is associated with an increased risk of adverse maternal and fetal outcomes.
Despite the high prevalence of anemia among pregnant women, poor medication adherence and inadequate understanding of prescribed therapy may limit treatment effectiveness. Pharmacists can play an important role in providing medication-related education, improving patients' understanding of their treatment, identifying barriers to adherence, and promoting appropriate medication use. However, evidence on pharmacist-led educational interventions to improve medication adherence and hemoglobin levels among anemic pregnant women in Pakistan remains limited.
Therefore, this randomized controlled trial will be conducted to evaluate the effect of a structured pharmacist-led educational intervention on medication adherence and hemoglobin levels among anemic pregnant women in District Chakwal, Punjab, Pakistan.
A total of 100 eligible pregnant women diagnosed with anemia will be recruited and randomly allocated into intervention and control groups. Participants in the intervention group will receive a structured pharmacist-led educational intervention in addition to routine care, while participants in the control group will receive routine antenatal care and standard anemia management.
Medication adherence and hemoglobin levels will be assessed at baseline and after the intervention. The study will determine whether pharmacist-led educational counseling improves medication adherence and hemoglobin levels compared with routine care.
Data will be analyzed using IBM SPSS Statistics version 26. A paired-sample t-test will be used to compare changes in continuous variables, particularly hemoglobin levels, between baseline and post-intervention assessments. McNemar's test will be used to assess changes in paired categorical variables, including medication adherence where appropriate. A p-value of <0.05 will be considered statistically significant.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Health Services Research
- 盲法
- None
入排标准
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Pregnant woman
- •Hb <11g/dl
- •Having Punjab domicile-
排除标准
- •Patients with co-morbidities
- •Patients with Hb >11g/dl
- •Outside the Punjab domicile
研究组 & 干预措施
Pre and post evaluation
Pharmacist-Led Anemia Counseling: Patients will receive individualized pharmacist-led counseling regarding anemia management, medication adherence, appropriate use of prescribed medicines, dietary measures, and strategies to improve quality of life. Outcomes will be assessed before the intervention and at one-month follow-up. Study Design: Single-arm, pre-post evaluation.
干预措施: Pharmacist-led counseling on anemia management (Other)
结局指标
主要结局
Change in hemoglobin concentration
时间窗: Baseline and one month after the pharmacist-led counseling intervention.
Description: Change in hemoglobin (Hb) concentration from baseline to one-month follow-up, measured in g/dL using a laboratory hemoglobin test.
Change in anemia severity
时间窗: Baseline and one month after the pharmacist-led counseling intervention.
Description: Change in anemia severity from baseline to one-month follow-up, categorized according to the participant's measured hemoglobin concentration using the predefined diagnostic criteria for anemia.
Medication adherence
时间窗: Time Frame: Baseline and one month after the intervention.
Description: Change in medication adherence from baseline to one-month follow-up, assessed using the \[name of your actual validated adherence scale/questionnaire\].
次要结局
未报告次要终点
研究者
Muhammad Abubakar
Associate Professor
Hamdard University