Comparison of Low Flow Anesthesia With and Without Initial High Flow Phase
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 80
- 试验地点
- 2
- 主要终点
- The time required to reach 0.7 MAC
研究概览
简要总结
The aim of the study is to compare the effectiveness of conventional low flow anesthesia (LFA) with initial high fresh gas flow ( 4L/min) for 10 minutes and LFA with fixed fresh gas flow rate (1L/min).
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •scheduled for surgery under general anesthesia with endotracheal intubation
排除标准
- •hemodynamic instability
- •emergency cases
- •expected anesthesia duration < 60 min
- •patient refusal
研究组 & 干预措施
Conventional group
After standart intravenous anesthesia induction end endotracheal intubation desflurane vaporizer will be set at 6% with fresh gas flow rate 4 L/min (50% O2, 50% air) until the EtAA concentration reaches 0.7 MAC (minimum alveolar concentration) Then, the desflurane vaporizer will be at a 1% higher value than the EtAA concentration required to achieve 0.7 MAC. And after 10 minutes fresh gas flow rate will be reduced to 1L/min.
干预措施: Conventional Low flow Anesthesia (Procedure)
Fixed Fresh Gas Flow Rate group
After standart intravenous anesthesia induction end endotracheal intubation desflurane vaporizer will be set at 18% with fresh gas flow rate 1 L/min (50% O2, 50% air) until the EtAA concentration reaches 0.7 MAC (minimum alveolar concentration) Then, the desflurane vaporizer will be at a 2% higher value than the EtAA concentration required to achieve 0.7 MAC.
干预措施: Low Flow Anesthesia with fixed fresh gas flow rate (Procedure)
结局指标
主要结局
The time required to reach 0.7 MAC
时间窗: perioperative
number of adjustments made to the vaporizer settings
时间窗: perioperative
MAC will be held between 0.6-0.8 with adjustments at the vaporizer
次要结局
- anesthetic agent consumption(perioperative)
研究者
MAHMUT ARSLAN
Assistant Professor
Kahramanmaras Sutcu Imam University