Which Treatment is Most Effective When Treating Vestibular Neuritis: Corticosteroid Treatment Alone or Combined Corticosteroid Treatment and Vestibular Rehabilitation?
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- Suppressing head impulse paradigm (SHIMP)
研究概览
简要总结
To investigate which treatment option (corticosteroid treatment alone or combined corticosteroid treatment and vestibular rehabilitation) is the most effective in patients diagnosed with vestibular neuritis.
详细描述
Patients diagnosed with vestibular neuritis will we consider for enrollment. Each patient will undergo randomization for a specific treatment.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age above 18 years of age
- •Medical history compatible with vestibular neuritis
- •Verification of vestibular neuritis with positive romberg test, pathological v-HIT and horizontal nystagmus with a rotatory component.
排除标准
- •Former medical history with vestibular dysfunction
- •Medical history or objective signs of cochlear dysfunction before, during or after onset of vestibular neuritis
- •Onset of symptoms 14 days before recruitment to the study
- •Focal neurological symptoms/signs
- •Contraindication to prednisolone treatment
- •Problem with participating in vestibular rehabilitation due to muscular-skeletal disease ect.
研究组 & 干预措施
Neuritis vestibularis (group 1)
Corticosteroid ("prednisolone")
干预措施: Corticosteroid (Drug)
Neuritis vestibularis (group 2)
Corticosteroid ("prednisolone") + vestibular rehabilitation
干预措施: Vestibular rehabilitation (Other)
Neuritis vestibularis (group 2)
Corticosteroid ("prednisolone") + vestibular rehabilitation
干预措施: Corticosteroid (Drug)
结局指标
主要结局
Suppressing head impulse paradigm (SHIMP)
时间窗: 6 month
SHIMP equipment will objectively quantify change of vestibular function.
Subjective visual vertical (SVV)
时间窗: 6 month
SVV test will objectively quantify the experienced spatial orientation as an indicator of visual and vestibular otolithic function
Video head impulse test (v-HIT)
时间窗: 6 month
v-HIT equipment will objectively quantify change of vestibular function.
Dizziness handicap inventory (DHI) questionnaire
时间窗: 6 month
Fulfillment of the questionnaire "Dizziness Handicap Inventory" (DHI) will quantify the level of experienced vertigo.
次要结局
未报告次要终点
研究者
Dan Dupont Hougaard
MD, Assistant Professor
Aalborg University Hospital