跳至主要内容
临床试验/NCT07256886
NCT07256886尚未招募不适用

Validation of the iCVS Model in Patients Admitted to the Intensive Care Unit: a Retrospective Study

Meir Medical Center0 个研究点目标入组 1,150 人开始时间: 2026年4月1日最近更新:

试验速览

阶段
不适用
状态
尚未招募
入组人数
1,150
主要终点
Optimization and validation of the ICVS model

研究概览

简要总结

One of the significant challenges in the care of critically ill patients in the intensive care unit is the assessment of hemodynamically unstable patients (shock states). The treating team uses data such as heart rate, arterial blood pressure, physical examination findings, etc. to assess the patient's cardiac output, peripheral vascular resistance, filling pressures and volumes, and vascular tone. These assessments are essential to assess the cause of shock (cardiac cause, hypovolemia, sepsis, etc.), but in many situations they are not easy to perform and require extensive knowledge and experience. Assessing the hemodynamic status of a critically ill patient based on dynamic mechanical models may be a good option for more accurate assessment of complex patients. Such a model is, for example, the iCVS model: it is a relatively simple, mechanical-dynamic model that can be used to understand complex cardiovascular conditions. This model requires only age and weight as initial data, and as dynamic data the model requires only an arterial blood pressure (AR) curve and a central venous pressure (CVP) curve. The model is based on the shape of the above curves for the purpose of analyzing the cardiovascular status of the patient. The model is suitable for both adults and children, although most of the work to date has been among pediatric intensive care patients.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • The relevant experiment population are all patients over age 18 admitted to the ICU in Meir -

排除标准

  • Missing data

结局指标

主要结局

Optimization and validation of the ICVS model

时间窗: 1 year

The goal of this experiment is to perform an initial optimization and validation of the ICVS model with respect to the following metrics: * detection time before blood pressure drop * clinical shock classification.

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

sara dichtwald

Dr

Meir Medical Center

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