Magnetocardiography for Precise Identification of the Site of Origin of Tachyarrhythmia
试验速览
- 阶段
- 不适用
- 入组人数
- 1,000
- 试验地点
- 1
- 主要终点
- Efficacy of MCG to detect the site of origin of Tachyarrhythmia using cardiac electrophysiology as a reference standard.
研究概览
简要总结
This is an exploratory research aiming to accurately identify the site of origin of tachyarrhythmia using Magnetocardiography (MCG), which will have guiding significance for early diagnosis, the formulation of treatment plans and preoperative positioning for radiofrequency ablation.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 79 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age 18-79 years old;
- •Those whose conditions are comparatively stable and who have been diagnosed by an attending physician （or physicians with higher qualifications） with paroxysmal supraventricular tachycardia, atrial tachycardia, atrial flutter, atrial fibrillation, or premature ventricular contractions, and who are capable of performing MCG and cardiac electrophysiologic examinations after evaluation.
- •Signed informed consent.
排除标准
- •Those with known structural heart disease such as cardiomyopathy and valvular disease;
- •Those with history of other cardiovascular diseases such as pulmonary embolism and aortic dissection;
- •Those with connective tissue diseases (lupus erythematosus, rheumatoid arthritis, dermatomyositis, polyarteritis nodosa, etc.) combined with cardiac complications;
- •Those with obvious abnormal thyroid function, severe anemia or other blood diseases and other diseases that obviously affect the circulating blood supply;
- •Those with Obese (BMI>30kg/cm2) or underweight (BMI<18kg/cm2);
- •Those with malignant tumors;
- •Professional athletes, pregnant or breastfeeding women, alcoholics;
- •Those with acute diseases or critical illnesses in other systems, such as acute or severe respiratory diseases, abnormal liver function or renal function, etc.;
- •Those with infectious diseases or communicable diseases;
- •Those who are unable or fail to perform magnetocardiography due to claustrophobia, physical impairment, etc.;
- •Unable to or fail to cooperate with the corresponding research requirements.
研究组 & 干预措施
Patients with atrial tachycardia
Patients with atrial tachycardia will receive dynamic ECG, MCG and cardiac electrophysiologic examinations.
干预措施: Magnetocardiography (Device)
Patients with atrial flutter
Patients with atrial flutter will receive dynamic ECG, MCG and cardiac electrophysiologic examinations.
干预措施: Magnetocardiography (Device)
结局指标
主要结局
Efficacy of MCG to detect the site of origin of Tachyarrhythmia using cardiac electrophysiology as a reference standard.
时间窗: 12 month course of the disease
Sensitivity, specificity, and area under the ROC curve are performed for assessing the efficacy.
次要结局
未报告次要终点