Comparison Between Negative Pressure Wound Therapy and Conventional Wound Dressings Before and After Split-Thickness Skin Grafting in Diabetic Foot Wounds
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- Time of complete healing
研究概览
简要总结
The aim of this thesis is to compare the efficacy of Vacuum assisted closure device versus conventional dressing before and after split thickness skin grafting in diabetic foot wounds.
详细描述
Negative pressure wound therapy is a new noninvasive technique for treating open wounds. It works by removing fluid from the wound bed, reducing edema, and encouraging the growth and perfusion of new granulation tissue.
Vacuum-Assisted Closure device (VAC) helps to remove fluid from open wounds through a sealed dressing and tubing which is connected to a collection container. Vacuum-assisted closure (VAC) can provide stable and persistent negative pressure, and there are several modes to choose from.
VAC has played an important role in helping to close wounds, controlling infection, promoting angiogenesis, increasing blood flow, and promoting granulation tissue growth in wounds. It is now widely applied in all kinds of acute, chronic, and special wounds with good therapeutic results. However, there is a need to pay attention to contraindications and complications of VAC when it is used, avoiding secondary damage due to improper treatment.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- None
入排标准
- 年龄范围
- 20 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age group 20-75 years.
- •Patients with diabetic foot wounds who are scheduled for skin grafting.
排除标准
- •Age <20 years or > 75 years.
- •An obvious septicemia.
- •Foot osteomyelitis.
- •Ulcer resulting from venous insufficiency.
- •Features of malignant ulcer.
- •Patients being treated with corticosteroids, immunosuppressive drugs.
- •Any other serious pre-existing cardiovascular, pulmonary or immunological disease.
结局指标
主要结局
Time of complete healing
时间窗: 1 month
Number of days needed for each patient for complete healing after operation
Period of hospitalization.
时间窗: 2 weeks
Number of days of patient hospitalization before and after grafting
Patient satisfaction of aesthetic outcome
时间窗: 5 months
Number of patients satisfied with the aesthetic result of the operation on a scale of 0-10
Functional outcome
时间窗: 5 months
Number of patients with full range of mobility at site of graft Vs number of patients with limited mobility
次要结局
未报告次要终点
研究者
Hady Khaled Elhossiny
Resident of plastic and reconstructive surgery, Sohag University hospital
Sohag University