Randomised trial to compare the clinical value of cyclosporin C12 and C2 monitoring after lung transplantation

Papworth Hospital NHS Trust (UK)0 个研究点目标入组 90 人开始时间: 2005年7月8日最近更新: 2018年7月30日

试验速览

2004 results presented at 24th International Society of Heart and Lung Transplantation https://www.jhltonline.org/article/S1053-2498(03)00838-6/fulltext 2. 2005 results presented at 25th International Society of Heart and Lung Transplantation https://www.jhltonline.org/article/S1053-2498(04)00744-2/fulltext

•90 patients lung transplant:
•1. Adult single or double lung and heart + lung transplant recipients (18 years and older)
•2. Patients receiving Neoral as primary immunosuppression

•1. Patients not giving voluntary, written informed consent to participate
•2. Re-transplantation
•3. Simultaneous kidney, pancreas, liver or bowel transplantation
•3. Urine output <50 ml/hour and/or serum creatinine =170 mmol/l at the most recent investigation prior to transplantation
•4. Renal replacement therapy or any form of renal support such as continuous veno-venous haemofiltration (CVVH) or dialysis before transplantation or within the first post-operative week
•5. Patients receiving tacrolimus or sirolimus as primary immuno-suppression in place of Neoral

发起方

Papworth Hospital NHS Trust (UK)