The Effects of a Daily Intake of Cod Residual Material Meal for 8 Weeks on Serum Lipids and Fatty Acids, Glucose Regulation and Body Composition in Lean, Active Adults: A Randomized Controlled Trial.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 70
- 试验地点
- 1
- 主要终点
- Lipid metabolism
研究概览
简要总结
A high intake of fish is associated with positive health effects, including prevention and treatment of chronic non-communicable diseases, such as cardiovascular diseases (CVDs) and type 2 diabetes. These health effects have traditionally been attributed to the omega-3 fatty acids in fatty fish, but recent studies have suggested that also fish proteins may improve biomarkers of metabolic disease. Intake of cod fillet have previously shown beneficial effects on blood lipids, glucose regulation and body composition in adults with overweight or obesity. Health effect of cod residual material from fillet production (i.e., head, backbone, skin, cutoffs and entrails) have so far not been investigated, but residuals from other fish species have shown promising effects on glucose regulation in rats. The main aim of the current study is to investigate the effects of cod residual meal on serum lipids and glucose regulation in healthy, physically active adults.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 20 Years 至 55 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •BMI ≥ 18.5 kg/m2
- •Fasting blood glucose ≤7 mmol/L
- •Physically active
- •Percent body fat, 5-25 % for men and 12-35 % for women
排除标准
- •Allergies towards fish, milk, egg, gluten
- •Tobacco use > 10 cigarettes (or snus) per day
- •Diseases affecting the heart, intestinal function, kidney function or insulin secretion
- •Medications targeting cholesterol -or glucose metabolism, hypertension
- •Use of dietary supplements
- •Pregnancy or lactation
结局指标
主要结局
Lipid metabolism
时间窗: 8 weeks
Lipids will be measured in fasting serum samples
次要结局
- Biomarkers related to glucose regulation(8 weeks)
- Body composition(8 weeks)
研究者
Oddrun Anita Gudbrandsen
Researcher, PhD
University of Bergen