Boxing Training Effects on Cardiovascular Risk, Quality of Life, Endothelial Function, and Blood Flow Patterns in Individuals With Elevated Blood Pressure or Stage 1 Hypertension
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 24
- 试验地点
- 1
- 主要终点
- Change from baseline brachial blood pressure after week six
研究概览
简要总结
The goal of this clinical trial is to determine whether boxing training reduces cardiovascular risk in elevated blood pressure or hypertension stage 1 individuals.
The main questions it aims to answer are (1) if boxing training reduces peripheral and central blood pressure and (2) if boxing training improves cardiovascular function in elevated blood pressure or hypertension stage 1 individuals.
Participants with elevated blood pressure or hypertension stage 1 will be randomly divided into a control group or an intervention group. The latter group will be involved in boxing training, 3 days per week for 6 weeks.
Researchers will compare clinical and cardiovascular outcomes between the control and the intervention group.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Care Provider)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •≥18 years old.
- •Systolic blood pressure between 120-139 mmHg and/or diastolic blood pressure between 80-89 mmHg obtained from 2 different days.
- •an estimated 10-year risk of CVD ≤10%, calculated by the ACC/AHA Pooled Cohort Equations.
- •no current participation in 3 or more days per week of endurance or resistance exercise training.
排除标准
- •non-controlled cardiac, pulmonary, or metabolic diseases.
- •smoking, consumption of nutritional supplements containing antioxidants.
- •any physical impairment to exercise.
研究组 & 干预措施
Boxing
The boxing training intervention will consist of three exercise sessions per week on nonconsecutive days for six weeks
干预措施: Boxing Training (Other)
Control
The control group will perform three days per week 10 minutes a flexibility intervention.
干预措施: Control flexibility (Other)
结局指标
主要结局
Change from baseline brachial blood pressure after week six
时间窗: pre-intervention and immediately after the intervention
Resting systolic and diastolic blood pressure (mmHg)
次要结局
- Nitric Oxide Bioavailability(pre-intervention and immediately after the intervention)
- Body Fat Percentage(pre-intervention and immediately after the intervention)
- Total Antioxidant Capacity (TAC) to assess oxidative stress(pre-intervention and immediately after the intervention)
- Lipid Profile(pre-intervention and immediately after the intervention)
- Weight(pre-intervention and immediately after the intervention)
- Central Blood Pressure(pre-intervention and immediately after the intervention)
- Vascular function(pre-intervention and immediately after the intervention)
- Plethysmography(pre-intervention and immediately after the intervention)
- Maximum Oxygen Uptake(pre-intervention and immediately after the intervention)
- Lean Mass(pre-intervention and immediately after the intervention)
- Quality of Life measured by the short-form 36 (SF-36)(pre-intervention and immediately after the intervention)
- Arterial Stiffness(pre-intervention and immediately after the intervention)
- C Reactive Protein (CRP) to assess inflammation(pre-intervention and immediately after the intervention)
- Interleukin-6 (IL-6) to assess inflammation(pre-intervention and immediately after the intervention)
- Tumor necrosis factor alfa (TNFα) to assess inflammation(pre-intervention and immediately after the intervention)
- Superoxide dismutase (SOD) to assess oxidative stress(pre-intervention and immediately after the intervention)
- 8-isoprostane to assess inflammation(pre-intervention and immediately after the intervention)
- Height(pre-intervention and immediately after the intervention)