跳至主要内容
临床试验/NL-OMON32412
NL-OMON32412已完成不适用

The effects of Acute Tryptophan Depletion in individuals with a history of depression with and without anger attacks - Serotonin and depression

niversiteit Leiden0 个研究点目标入组 40 人开始时间: 待定最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
40

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional

入排标准

年龄范围
18 至 99(—)

入选标准

  • - Age between 18 and 65 years; - Meeting DSM-IV criteria for past depression as a primary diagnosis; - Having at least 2 episodes of past depression OR having at least one first-degree relative with recurrent MDD; - A Hamilton depression rating scale (HDRS)-score lower than 10 OF MADRS < 12; - Depression in remission for at least 3 months; - Free of antidepressant medication for at least 1 month or for more than 5 elimination half-lives of the drug, whichever is more.

排除标准

  • - Major physical illness; - Substance abuse within the last 3 months; - Lactation
  • - Pregnancy; - History or current Psychotic Disorder or Bipolar Disorder; - Using medication likely to affect CNS function, incl. benzodiazepines

研究者

发起方
niversiteit Leiden

相似试验

已完成
不适用
Pilot study to investigate if reducing serotonin levels in patients with chronic fatigue syndrome is effective.Pathophysiology of chronic fatigue syndromeNervous System DiseasesPostviral fatigue syndrome
ISRCTN07518149Radboud University Nijmegen Medical Center (Netherlands)5
已完成
不适用
Tryptophan depletion in patients with selective serotonin reuptake inhibitor-remitted generalised anxiety disorder or obsessive compulsive disorder.Obsessive compulsive disorder (OCD)Mental Health - Anxiety
ACTRN12609000170224niversity of Western Australia8
尚未招募
不适用
Alterations of tryptophan metabolism during acute aerobic endurance exercise in blood serum and circulating immune cells.Physiological study in healthy participants. No health problem will be investigated
DRKS00029105TU Dortmund, Institut für Sport und Sportwissenschaft, Arbeitsbereich für Leistung und Gesundheit (Sportmedizin)14
已完成
不适用
The effect of tryptophan-supplement intake at breakfast on melatonin secretion at nightHealthy adults
JPRN-UMIN000024121Fukuoka Women&#39;s University12
已完成
不适用
The effects of dietary tryptophan manipulation on serotonin and parameters of motor control on healthy adultseurotransmitter level imbalanceProtein supplementationNeurotransmitter level imbalanceNeurological - Studies of the normal brain and nervous systemMusculoskeletal - Normal musculoskeletal and cartilage development and functionMental Health - Studies of normal psychology, cognitive function and behaviour
ACTRN12621001664831Karen Mackay16