跳至主要内容
临床试验/NCT07634250
NCT07634250尚未招募不适用

Association Between Mental Health Status and Periodontitis Among Probable Bruxers

Postgraduate Institute of Dental Sciences Rohtak1 个研究点 分布在 1 个国家目标入组 110 人开始时间: 2026年6月1日最近更新:
适应症

试验速览

阶段
不适用
状态
尚未招募
入组人数
110
试验地点
1

研究概览

简要总结

The goal of this observational study is to learn how mental health affects periodontal health in people having teeth grinding (bruxism).

The main questions it aims to answer are:

Does poor mental health increase the risk of periodontitis in people with teeth grinding? Does stress link teeth grinding and periodontitis?

Participants are people who likely have teeth grinding(bruxism) and periodontitis

Participants will:

Answer questions about their mental health, including stress Get a periodontal health status check

Teeth grinding(Bruxism) can occur due to stress, smoking, alcohol use, and bite problems. Stress may affect muscle activity and lead to teeth grinding. It can also weaken the body's defense and lead to poor oral care. This may worsen periodontal health.

详细描述

Stress is related to emotional and physiological reactions when there is a lifetime event conflict that exceeds the individual's ability to deal effectively with the situation.

Psychological stress is generally recognized as a potential cofactor in the pathogenesis of infectious disease. It can trigger immune responses that favor the occurrence or exacerbation of changes in the oral cavity, such as periodontitis. It can directly impair the periodontal status through various biological mechanisms: variation in the gingival fluid, production of interleukin IL1, IL-6, reduction of polymorphonuclear leukocytes and phagocytosis, and decreased lymphocyte production and antibody production, as well as through changes in behavior related to health, such as oral hygiene, smoking habit and diet.

Stress evokes emotional and physiologic reactions and is an important modifiable risk factor for both mental and physical illnesses.

Periodontitis is characterized by progressive destruction of the tooth-supporting apparatus causing loss of support which manifests through clinical attachment loss (CAL), radiographically assessed alveolar bone loss, presence of periodontal pocket and gingival bleeding.

Based on the ecologic plaque hypothesis, periodontal diseases result from environmental changes to the oral habitat. Marsh considers that the selection of ''pathogenic'' bacteria is directly coupled to changes in the environment.

研究设计

研究类型
Observational
观察模型
Other
时间视角
Cross Sectional

入排标准

年龄范围
30 Months 至 50 Months(Child)
性别
All
接受健康志愿者

入选标准

  • Adult periodontitis patients with age group 30-50 years diagnosed with probable bruxism.
  • Presence of minimum 20 teeth excluding third molars.

排除标准

  • History of systemic disease such as diabetes or autoimmune disease
  • History of drugs having the potential impact on periodontal status like phenytoin, cyclosporin, calcium-channel blockers or antidepressant drugs.
  • Pregnant or lactating females.
  • Post-menopausal women.
  • Patients diagnosed with temporomandibular disorders- pain and tenderness in the masticatory muscles

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

Loading locations...

相似试验