Diagnostic Value of D-dimer/Fibrinogen Ratio in Patients With Acute Aortic Dissection
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 159
- 试验地点
- 2
- 主要终点
- Acute aortic dissection
研究概览
简要总结
Acute aortic dissection is rare but potentially life-threatening disease with an incidence of 5-30 cases per million, annually. Therefore prompt diagnosis is crucial. D-dimer values have been shown to be useful in the diagnosis of acute aortic dissection. Fibrinogen levels have been shown to be low, normal or high in individuals with acute aortic dissection. This study aims to investigate whether D-dimer/fibrinogen ratio can be valuable for diagnosis of acute aortic dissection.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Diagnosis of acute aortic dissection
- •Diagnosis of acute pulmonary embolism
- •Diagnosis of non-cardiac chest pain
排除标准
- •Any etiology of chest pain other than acute aortic dissection, acute pulmonary embolism, or non-cardiac chest pain
- •Participants who do not give consent for enrollment
结局指标
主要结局
Acute aortic dissection
时间窗: 24 hours
Diagnosis of acute aortic dissection confirmed by contrast enhanced computed tomography, magnetic resonance imaging, echocardiography or aortography
次要结局
未报告次要终点
研究者
Ahmet Can Topcu
Director of Department of Cardiovascular Surgery
Dr. Lutfi Kirdar Kartal Training and Research Hospital