NCT05002764Unknown不适用

Differential Vulnerability of Individual Thalamic Nuclei: Toward New Biomarkers in Multiple Sclerosis

University Hospital, Bordeaux1 个研究点分布在 1 个国家目标入组 2,000 人开始时间: 2021年7月1日最近更新: 2021年8月12日

研究概览

简要总结

The thalamus is composed of several nuclei interlocked in a complex anatomy. In multiple sclerosis (MS), the thalamus can be altered due to disconnection by white matter lesions and due to direct damages that could be partly mediated by CSF. Due to such pathophysiology and complex anatomy, some nuclei could be more vulnerable to multiple sclerosis than others. We will test this hypothesis by using a new algorithm to automatically segment several nuclei that we will be applied to the French national MS database

研究设计

研究类型: Observational
观察模型: Cohort
时间视角: Other

入排标准

年龄范围: 18 Years 至 —（Adult, Older Adult）
性别: All
接受健康志愿者: 否

入选标准

未提供

排除标准

未提供

结局指标

主要结局

Volume of thalamic nuclei

时间窗: At inclusion in the cohort

Volume of individual thalamic nuclei according to disease duration.

次要结局

未报告次要终点

研究者

发起方

University Hospital, Bordeaux

申办方类型

Other

责任方

Sponsor

研究点 (1)

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