Zinc Supplementation Impact on Child Mortality--Nepal
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 发起方
- 入组人数
- 58,000
- 试验地点
- 5
- 主要终点
- Death among children 1-36 months of age
研究概览
简要总结
The purpose of this study is to determine whether daily supplementation of young children in Nepal with either zinc, iron-folic acid, or both can reduce mortality and morbidity. Young children in Nepal have numerous nutritional deficiencies and high rates of morbidity and mortality. Zinc and/or iron supplementation may be a cost-effective method for reducing these risks.
详细描述
Mortality rates among preschool age children in Nepal and many other developing countries remain high despite significant progress made over the past 20 years. There remain significant nutritional deficiencies in these populations, especially important are vitamin and mineral deficiencies.
Comparisons: In this study, we are comparing the morbidity and mortality experience for children 1-36 months of age randomized to one of four daily supplementation regimens: placebo, zinc alone, iron-folic acid alone, zinc + iron-folic acid.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Factorial
- 主要目的
- Prevention
- 盲法
- Double
入排标准
- 年龄范围
- 1 Month 至 36 Months（Child）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •All children 1-35 months of age living in 30 Village Development Committees of Sarlahi District in southern Nepal.
排除标准
- •Parent refusal
结局指标
主要结局
Death among children 1-36 months of age
次要结局
- Incidence rates of selected morbidities including diarrhea, dysentery, acute respiratory infections