Epidemiological Investigation of HIV-infected Patients Complicated With Liver Disease in Zhejiang Province
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 3,000
- 试验地点
- 1
- 主要终点
- Prevalence of liver disease in PLWH
研究概览
简要总结
In Highly Active Antiretroviral Therapy era, fatty liver has become an important cause of liver function damage in people living with HIV (PLWH). There are a large number of PLWH in China who are infected with hepatitis B virus and hepatitis C virus. HIV, hepatitis B virus, hepatitis C virus, drugs, alcohol, etc. affect each other, which makes the cause, diagnosis, and treatment of liver function damage in PLWH complicated in China.
The investigators plan to conduct a large-scale questionnaire survey among PLWH in Zhejiang Province to assess liver function, detect liver Injuries early, and analyze HIV, hepatitis B virus, hepatitis C virus, anti-HIV drugs, alcohol and other factors associate with liver injuries in PLWH, to provide basis for the treatment and prevention of liver disease in PLWH in eastern China.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age ≥18 years old;
- •Non-hospitalized patients diagnosed with HIV infection;
- •Sign the informed consent voluntarily.
排除标准
- •Severe active infection requiring parenteral antibiotics or antifungal treatment within 30 days before the assessment;
- •Other major chronic diseases that may affect health-related quality of life, such as extrahepatic malignant tumors;
- •Psychotic patients, patients with severe cognitive or neurological deficits;
- •Women during pregnancy and lactation;
- •Those who refuse to sign informed consent.
结局指标
主要结局
Prevalence of liver disease in PLWH
时间窗: 2020-12-31
The overall prevalence of liver disease in PLWH and the prevalence of hepatitis B, C, and fatty liver
次要结局
未报告次要终点