Automated Breast Radiation Therapy Using an MR-Guided Process
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 63
- 试验地点
- 1
- 主要终点
- Time between planning of Radiation treatment and the start of radiotherapy
研究概览
简要总结
In the proposed research study, we are investigating the feasibility of integrating automated planning tools to MR images acquired using a novel MR-guided linac, for on-line adaptive radiation treatment. However, these on-line automation tools require further technical refinement and clinical validation. The goal of this research proposal is to develop an on-line MR-guided radiation therapy process for adapting breast IMRT treatment. Such an approach will provide early stage breast cancer patients timely access to high-quality adaptive treatments without exposure to additional ionizing radiation.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Patients who will receive standard two-field tangential whole breast radiation therapy with dose prescription of 4240 cGy in 16 fractions, 5000 cGy in 25 fractions or 4000 cGy in 16 fractions.
- •Female patients with any stage of breast cancer.
- •Patients with prior treatment such as surgery or chemotherapy for any type of cancer.
- •Able to provide a written informed consent.
- •≥ 18 years of age.
排除标准
- •Patients who will not receive 4240 cGy in 16 fractions, 5000 cGy in 25 fractions, or 4000 cGy in 16 fractions
- •Patients who received partial breast radiation and not the standard dose.
- •Patients who are unable to provide informed consent.
- •< 18 years of age.
研究组 & 干预措施
IMRT + CT + MR scan
干预措施: IMRT + CT + MR scan (Other)
结局指标
主要结局
Time between planning of Radiation treatment and the start of radiotherapy
时间窗: 3 years
The effect of breathing on the position of the heart and lung in treatment plans
时间窗: 3 years
次要结局
未报告次要终点