NL-OMON26840尚未招募不适用
HEBE III: A prospective, randomised, double blind, placebo controlled clinical study to examine the effects of a single bolus erythropoietin on left ventricular function in patients with an acute myocardial infarction.
Inter Cardiological Institute NetherlandsVan Buchem Stichting (UMCG)0 个研究点目标入组 400 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 400
研究概览
简要总结
/A
研究设计
- 研究类型
- Interventional
入排标准
入选标准
- •Successful primary PCI (TIMI 2/3) for a first acute myocardial infarction, diagnosed by:
- •1. Chest pain suggestive for acute myocardial infarction;
- •2. Symptom onset < 12 hour after hospital admission, or < 24 hour in case ongoing ischemia;
- •3. ECG with ST-T segment elevation > 1 mV in 2 or more leads;
- •4. TIMI flow 0/1 before primary PCI on diagnostic coronary angiography.
排除标准
- •1. Hemoglobin levels > 10.6 mmol/L;
- •2. Anticipated additional revascularisation within 4 months;
- •3. Cardiogenic shock;
- •4. Presence of other serious medical conditions;
- •5. Pregnancy/breast feeding;
- •6. Malignant hypertension;
- •7. End stage renal failure (kreatinin > 220 micromol/l);
- •8. Previous treatment with rh-EPO;
- •9. Blood transfusion <12 weeks prior to randomisation;
- •10. Allergy against rh-EPO;
- •11. Polycytemia verae;
- •12. Previous acute myocardial infarction;
- •13. Concomitant inflammatory or malignant disease;
- •14. Recent trauma or major surgery;
- •15. Unwilling to sign informed consent;
- •16. Contra-indications for MRI (pacemaker and other metal subjects).
研究者
相似试验
进行中（未招募）
不适用
HEBE III: A prospective, randomised, double blind, placebo controlled clinical study to examine the effects of a single bolus erythropoietin on left ventricular function in patients with an acute myocardial infarction - HEBE IIIPatients with a successful primary PCI (TIMI 2/3) for a first acute myocardial infarctionEUCTR2006-002940-28-NLICI400
招募中
3 期
HEBE III: A prospective, randomised, clinical study to examine the effects of a single bolus erythropoietin on left ventricular function in patients with an acute myocardial infarctiomyocardial infarctionheart attack10011082NL-OMON30616niversitair Medisch Centrum Groningen466
已完成
3 期
A trial looking at Hyperbaric Oxygen (HBO) Treatment for people who have long-term side effects following radiotherapy for pelvic cancerCancerISRCTN86894066Institute of Cancer Research (UK)84
已完成
3 期
A phase III multicentre double blind randomised trial of celecoxib versus placebo in primary breast cancer patientsCancerBreast cancerISRCTN48254013Imperial College of Science and Technology (UK)2,639
招募中
4 期
C4951012 - BHV3000-407: A Phase 4, Randomized, Double-blind, Placebo controlled Study to Evaluate the Efficacy and Tolerability of Rimegepant for the Prevention of Migraine in Adults with a History of Inadequate Response to Oral Preventive Medications2024-513270-21-00Pfizer Inc.470