Impact of a Family History of Hypertension and Physical Activity on Left Ventricular Mass
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 74
- 主要终点
- Left Ventricular Mass
研究概览
简要总结
This is a retrospective analysis of data collected within two previous studies. The data has been combined and used to investigate the impact of having a family history of hypertension on left ventricular muscle mass with and without controlling for moderate and vigorous intensity physical activity frequency per week. The hypothesis was that in a sample of mostly active participants, no differences in left ventricular mass between family history of hypertension groups would be observed, but the positive family history of hypertension group would have elevated left ventricular mass compared to the negative family history of hypertension group following statistical control of activity frequency.
详细描述
A positive family history of hypertension (FHH) (+FHH) is associated with elevated left ventricular mass (LVM). Regular physical activity (PA) may eliminate differences in LVM between +FHH and negative family history of hypertension (-FHH) adults. PURPOSE: To determine if a +FHH is associated with a greater LVM compared to a -FHH group within a sample of young, mostly active healthy adults with and without statistically controlling for PA. METHODS: Healthy young (18-32yrs) participants self-reported FHH status and habitual moderate and vigorous PA frequency. Participants then underwent an echocardiogram.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 32 Years(Adult)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Generally healthy
排除标准
- •Known hypertension, cardiovascular disease, current pregnancy, current infectious disease, diabetes mellitus, kidney disease, a history of cancer, pulmonary disease, history of a stroke, obesity (for most people this means a body mass index greater than 30), or any life threatening chronic conditions
结局指标
主要结局
Left Ventricular Mass
时间窗: Day 2
Muscle mass in grams of the left ventricle of the heart as estimated by ultrasound.
次要结局
未报告次要终点
研究者
Evan Matthews
Associate Professor
Montclair State University
