To evaluate the incidence of new onset diabetes in acute coronary syndrome patients on statins and evaluate the dose related risk.

Statins have been linked to new onset diabetes. No randomised control trail is there to prove definite causation. We plan to study acute coronary syndrome patients who receive high dose statins and look at blood sugar and insulin resistance to determine their effect on inducing new onset diabetes. We study different statins : atorvastatin , simvastatin , rosuvastatin . pitavastatin , parvastatin to see which has highest effect on inducing new onset diabetes. The study participants are encouraged to maintain healthy diet and body weight over duration of study. After 6 months of intensive high dose statin the dose of statin will be reduced to minimal required and participants followed up over next 6 months. The change in blood sugar levels from baseline to highest dose of statin at 6 month and minimal dose of statin at 1 year of start of study will be assessed. Incidence of new onset diabetes and cardiovascular events will be recorded.