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临床试验/NCT03905226
NCT03905226已完成不适用

Development of a Predictive Algorithm for the Risk of Rehospitalization of Patients With Heart Failure

Fondation Hôpital Saint-Joseph1 个研究点 分布在 1 个国家目标入组 1,486 人开始时间: 2019年1月12日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
1,486
试验地点
1
主要终点
Number of readmissions

研究概览

简要总结

Heart failure is a chronic disease whose prevalence, due to the aging of the population, is increasing. In France, the prevalence of this pathology is 2.3% (it reaches 10% in the over 75 years) and affects nearly a million patients.

The rehospitalization of patients with heart failure affects 25% of patients within 1-3 months of hospital discharge, and 66% at 1 year while 75% of hospitalizations are preventable. These readmissions result in decreased quality of life and increased mortality; from an economic point of view, hospitalization accounts for 70% of expenses related to the management of heart failure. Avoiding rehospitalization is therefore a major public health issue. The current predictive scores remain perfectible, even though risk factors for readmission have already been the subject of numerous studies. The identification of patients at risk of rehospitalization is still an issue, especially for patients with preserved left ventricular ejection fraction. Targeting patients requiring appropriate care remains an issue.

The rise of innovative statistical techniques around Big Data in health opens new perspectives for the scientific exploitation of data available in electronic medical records, for example in the field of prediction. This study aims to explore the risk of rehospitalization in heart failure patients by analyzing routine data collected in medical records and by mobilizing artificial intelligence algorithms. A review of the literature confirms the innovative nature of such an approach: the majority of the studies identified implemented a prospective collection of data; only 20% of the studies mobilized the medical file; no French study used the new machine learning algorithms.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者
否

入选标准

  • •Patients older than 18 years
  • •Patients with heart failure hospitalized in the cardiology department ath GHPSJ between january 2015 to december 2018

排除标准

  • •Patient opposing the use of his data for this research
  • •Patient under tutorship or curatorship
  • •Patient deprived of liberty

结局指标

主要结局

Number of readmissions

时间窗: Year 1

Comparison of the number of readmissions predicted to the number actually observed with calculation of the sensitivity and specificity of the model at the validation phase.

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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