Effects of Neurodynamic Interventions to Multimodal Physical Therapy in Patients With Multiple Sclerosis
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 32
- 试验地点
- 1
- 主要终点
- Changes in pressure pain sensitivity
研究概览
简要总结
A randomized, parallel-group, clinical trial will be conducted to compare the immediate effects of the inclusion of a neurodynamic intervention into a multimodal physiotherapy program on pressure pain sensitivity, pain and manual dexterity in patients with multiple sclerosis
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •a diagnosis of multiple sclerosis according to the modified McDonald criteria;
- •symptoms of paresthesia and lack of sensitivity in the upper extremity;
- •Expanded Disability Status Scale (EDSS) between 0 and 6.5 points;
- •absence of cognitive deficit.
排除标准
- •any exacerbation of multiple sclerosis during the previous 3 months;
- •previous hand surgery or steroid injections treatment in the upper extremity;
- •multiple diagnoses on the upper extremity (e.g., cervical radiculopathy);
- •cervical, shoulder, or upper extremity trauma;
- •other comorbid musculoskeletal medical conditions;
- •mini-mental state examination <25
研究组 & 干预措施
Physical Therapy
Patients will receive 5 session of multimodal physiotherapy treatment of 30min duration including low-load strength exercises, soft tissue mobilization and muscle-tendon stretching exercises twice per week.
干预措施: Physical Therapy (Other)
Physical Therapy plus neurodynamic
Patients will receive 5 session of multimodal physiotherapy treatment of 30min duration including low-load strength exercises, soft tissue mobilization and muscle-tendon stretching exercises twice per week. In addition, they will also receive bilateral nerve slider neurodynamic interventions targeting the median, ulnar and radial nerves.
干预措施: Physical Therapy plus Neurodynamic (Other)
结局指标
主要结局
Changes in pressure pain sensitivity
时间窗: Baseline and one week after the last treatment session
Pressure pain threshold over the median, ulnar and radial nerves, second metacarpal and tibialis anterior
次要结局
- Changes in upper extremity pain intensity before and after the intervention(Baseline and one week after the last treatment session)
- Changes in light touch detection threshold(Baseline and after treatmentBaseline and one week after the last treatment session)
- Changes in manual dexterity(Baseline and one week after the last treatment session)
研究者
César Fernández-de-las-Peñas
Director of Department
Universidad Rey Juan Carlos