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临床试验/CTRI/2026/01/101200
CTRI/2026/01/101200尚未招募3 期

Comparison of External Oblique and Rectus Abdominis Plane (EXORA) block with Subcostal Transverse Abdominis Plane (TAP) Block for post operative Analgesia in Laparoscopic Cholecystectomy

DR SHALMALEE SARKAR1 个研究点 分布在 1 个国家目标入组 72 人开始时间: 2026年1月30日最近更新:

试验速览

阶段
3 期
状态
尚未招募
发起方
入组人数
72
试验地点
1

研究概览

简要总结

Comparison of EXORA Block and Subcostal TAP Block for Postoperative Analgesia in Laparoscopic Cholecystectomy.

In recent years, regional anaesthesia, particularly abdominal wall blocks, has become a key component of multimodal analgesia due to their opioid-sparing effects and efficacy in managing postoperative pain. One such technique, the subcostal transversus abdominis plane (TAP) block, involves injecting local anaesthetic between the internal oblique and transversus abdominis muscles to target the anterior branches of thoracic spinal nerves (T6–T12). It has demonstrated effectiveness in providing analgesia for upper abdominal surgeries, including laparoscopic gallbladder removal, by covering the dermatomes linked to surgical and visceral pain in that area.

More recently, a novel block known as the External Oblique and Rectus Abdominis Plane (EXORA) block has been introduced. This technique targets the interfascial plane between the external oblique and rectus abdominis muscles, aiming to block the anterior cutaneous branches of thoracoabdominal nerves (T6–T9) that innervate the gallbladder and upper abdominal wall. The local anaesthetic is administered between these two muscles to potentially offer more localized pain relief in the upper abdominal region. Although promising, there is currently limited clinical research directly comparing its effectiveness to that of the subcostal TAP block.

The present study seeks to compare EXORA and subcostal TAP blocks in the context of postoperative pain relief, need for additional analgesics, and overall patient satisfaction following laparoscopic cholecystectomy. This comparison aims to determine whether EXORA block can be considered a viable or even superior alternative to the more established subcostal TAP technique in routine surgical practice.

研究设计

研究类型
Interventional
分配方式
Randomized
盲法
Participant and Investigator Blinded

入排标准

年龄范围
18.00 Year(s) 至 65.00 Year(s)(—)
性别
All

入选标准

  • Patients aged 18 to 65 years- ASA physical status classification I or II- Patients scheduled to undergo elective laparoscopic cholecystectomy.
  • BMI less than 35 kg/m²- Patients who provide written informed consent to participate in the study.

排除标准

  • Patients unwilling to participate- Known allergy to local anaesthetic agents- Coagulopathy or those on anticoagulation therapy- Local infection at the injection site- History of chronic pain or current opioid usage- Conversion from laparoscopic to open cholecystectomy- Pregnant women.

研究者

发起方
DR SHALMALEE SARKAR
申办方类型
Government medical college
责任方
Principal Investigator
主要研究者

Dr Shalmalee Sarkar

Command Hospital Eastern Command

研究点 (1)

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