ACTRN12620001295932招募中2 期
PeRiopErative Penicillin/Cephalosporin AlleRgy TEsting - A phase II feasibility/safety randomised control trial to empower anaesthetists to risk stratify and de-label antibiotic allergy labels in the perioperative period using digital health solutions.
试验速览
- 阶段
- 2 期
- 状态
- 招募中
- 入组人数
- 150
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Treatment
- 盲法
- Blinded (masking used)
入排标准
- 年龄范围
- 18 Years 至 o limit（—）
- 性别
- All
入选标准
- •Patients aged 18 years and above that are reviewed in the perioperative assessment clinic under the care of a surgerical unit, having a reported penicillin or cephalosporin allergy label, and will require intravenous antibiotic therapy in planned perioperative care.
排除标准
- •Patients aged < 18 years
- •Patients currently receiving beta-lactam antibiotic therapy
- •Previous referral or assessment by a specialist for beta-lactam allergy
- •Under the current care of an Allergy/Immunology specialist
- •Require non-beta-lactam antibiotics for an infection or colonization with an organism resistant to beta-lactam (eg MRSA, ESBL producing gram negatives)
- •Emergency or trauma surgery
- •Contraindication for oral penicillin provocation
- •Patients receiving more than 10mg of prednisolone or
- •equivalent daily
- •Patients receiving antihistamine therapies
- •Patients with a history of drug-associated anaphylaxis or idiopathic urticaria/anaphylaxis
研究者
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