Minimum Cuff Pressure to Prevent Gas Leakage During Mechanical Ventilation in Laryngomicrosurgery - Pilot Study -
试验速览
- 阶段
- 不适用
- 入组人数
- 46
- 试验地点
- 1
- 主要终点
- Cuff pressure
研究概览
简要总结
The goal of this prospective observational study is to investigate minimum cuff pressure to prevent gas leakage during mechanical ventilation in laryngomicrosurgery.
详细描述
It has been well known that cuff pressure should be adequately limited to prevent ischemic injury of tracheal mucosa, which is about 20-30 mmHg. However, higher cuff pressure that 20-30 mmHg might be required to prevent gas leakage during general anesthesia for laryngomicrosurgery.
The hypothesis of this study is that the required cuff pressure to prevent gas leakage from mechanical ventilation during general anesthesia for laryngomicrosurgery, and there will be no damage from the required cuff pressure because of short time of surgery.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients who is scheduled for laryngomicrosurgery due to simple vocal cord cyst or nodule
排除标准
- •Who doesn't agree to enroll
- •do not use a reinforced tracheal tube of internal diameter of 5.5 mm for male patient
- •do not use a reinforced tracheal tube of internal diameter of 5.0 mm for female patient
结局指标
主要结局
Cuff pressure
时间窗: intraoperative
the required cuff pressure to prevent gas leakage from mechanical ventilation during general anesthesia for laryngomicrosurgery
post operative complication
时间窗: from end of surgery to 1-2 weeks after surgery
any postoperative symptoms associated with cuff pressure such as hoarsness, dyspnea
次要结局
未报告次要终点