Root-Level Diagnostic Sensitivity of the Femoral Stretch Test in Patients With L2, L3, or L4 Nerve Root Compression: A Prospective Observational Study
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 120
- 试验地点
- 2
- 主要终点
- Root-Level Sensitivity of the Femoral Stretch Test for L2, L3, and L4 Nerve Root Compression
研究概览
简要总结
This prospective observational study aims to evaluate the sensitivity of the femoral stretch test in patients with unilateral, single-root L2, L3, or L4 nerve root compression and to determine whether test positivity differs according to the affected nerve root.
Patients with unilateral radicular symptoms and magnetic resonance imaging-confirmed single-root compression involving the L2, L3, or L4 nerve root who are scheduled to undergo transforaminal epidural steroid injection as part of routine clinical care will be included. The decision to perform transforaminal epidural steroid injection will be made independently of participation in the study.
Before the procedure, the femoral stretch test, pain intensity, neuropathic pain characteristics, dermatomal concordance of symptoms, and relevant magnetic resonance imaging findings will be recorded. The femoral stretch test and pain intensity will be reassessed 1 hour after the procedure. The study will primarily evaluate the sensitivity of the femoral stretch test for L2, L3, and L4 nerve root involvement and will also assess changes in test findings following transforaminal epidural steroid injection.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Months 至 —（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with a diagnosis of lumbar radicular pain based on medical history, physical examination, and imaging findings.
- •Patients with unilateral L2, L3, or L4 nerve root involvement who are scheduled to undergo single-level, unilateral transforaminal epidural steroid injection targeting the corresponding nerve root.
排除标准
- •Presence of diabetes mellitus or other medical conditions that may cause polyneuropathy.
- •Presence of active radicular pain originating from lumbosacral nerve roots other than L2, L3, or L
- •Unavailability of relevant radiological imaging.
- •Cognitive impairment that may interfere with clinical assessment.
- •Pregnancy.
- •Presence of local or systemic infection.
研究组 & 干预措施
L2 Nerve Root Compression Cohort
Patients with unilateral, magnetic resonance imaging-confirmed single-root L2 nerve root compression and clinically concordant radicular symptoms who are scheduled to undergo transforaminal epidural steroid injection as part of routine clinical care. Femoral stretch test findings and pain intensity will be recorded before and after the procedure.
L3 Nerve Root Compression Cohort
Patients with unilateral, magnetic resonance imaging-confirmed single-root L3 nerve root compression and clinically concordant radicular symptoms who are scheduled to undergo transforaminal epidural steroid injection as part of routine clinical care. Femoral stretch test findings and pain intensity will be recorded before and after the procedure.
L4 Nerve Root Compression Cohort
Patients with unilateral, magnetic resonance imaging-confirmed single-root L4 nerve root compression and clinically concordant radicular symptoms who are scheduled to undergo transforaminal epidural steroid injection as part of routine clinical care. Femoral stretch test findings and pain intensity will be recorded before and after the procedure.
结局指标
主要结局
Root-Level Sensitivity of the Femoral Stretch Test for L2, L3, and L4 Nerve Root Compression
时间窗: Baseline
The sensitivity of the femoral stretch test will be calculated separately in patients with unilateral, Magnetic Resonance Imaging-confirmed single-root L2, L3, and L4 nerve root compression. Root-level sensitivities will be compared to determine whether the diagnostic sensitivity of the test differs according to the affected nerve root.
次要结局
- Change in Femoral Stretch Test Positivity Following Transforaminal Epidural Steroid Injection(Baseline and 1 hour post-procedure)
- Change in Pain Intensity Following Transforaminal Epidural Steroid Injection(Baseline and 1 hour post-procedure)
- Association Between Femoral Stretch Test Positivity and Magnetic Resonance Imaging Nerve Root Compression Severity(Baseline)
- Association Between Femoral Stretch Test Positivity and Neuropathic Pain Characteristics(Baseline)
研究者
Nurbanu Hindioglu Dogan
Principal Investigator
Marmara University