Effects of Exercise Snacks on Physical Health and Cognitive Function in Individuals With Intellectual Disabilities
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 24
- 试验地点
- 1
- 主要终点
- Changes in cognitive function assessed by cognitive test battery
研究概览
简要总结
Intellectual disability (ID) is a neurodevelopmental disorder accompanied by sedentary lifestyles, which worsens cognitive function and physical health. Short-duration high-frequency exercise snacks (ES) may be a feasible intervention for adults with ID. This randomized controlled crossover study aims to explore the acute effects of exercise snacks, conventional HIIT and daily routine control on cognitive function, stereotyped behaviors and prefrontal cortex activation in adults with mild to moderate ID. All participants will receive three intervention conditions with a 1-week washout period between each trial. Neurophysiological indicators including EEG and heart rate variability will be measured to reveal the underlying mechanisms.
详细描述
Background:
Adults with intellectual disability commonly maintain sedentary daily routines, resulting in progressive decline in physical fitness and cognitive performance. Traditional long-duration exercise interventions are difficult to implement for this population due to behavioral and cognitive limitations. Exercise snacks, consisting of repeated ultra-short exercise bursts, are easy to carry out and show promising benefits for cognition.
Methods:
A randomized controlled crossover design will be adopted. Twenty-four adults aged 18-35 years with mild to moderate ID will complete three conditions in random sequence: no-exercise control, high-intensity interval training (HIIT), and exercise snacks (ES). A 1-week washout interval separates different interventions.
Intervention protocols:
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 35 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Aged 18-35 years old;
- •Clinically diagnosed mild to moderate intellectual disability;
- •Able to follow simple verbal instructions and complete exercise protocols;
- •No contraindications for moderate physical activity confirmed by medical inquiry;
- •Participants or legal guardians provide written informed consent;
- •Maintain stable daily routine and do not participate in other structured exercise programs during the trial.
排除标准
- •Severe physical disabilities, orthopedic injury or neurological disorders that restrict movement;
- •History of cardiovascular disease, uncontrolled hypertension or other exercise contraindications;
- •Current psychiatric medication that significantly affects motor or cognitive function;
- •Inability to cooperate with EEG and physiological signal collection;
- •Participation in other interventional studies within the past 3 months.
研究组 & 干预措施
Arm 1
Participants maintain their usual daily activities without additional prescribed exercise. Daily physical activity will be recorded throughout the intervention period.
Arm 2（Exercise Snacks）
Twice-daily short-bout exercise snacks. Each session includes 5 sets of 6-second high-knee exercise with 9 seconds rest between sets.
干预措施: Exercise Snacks (Behavioral)
Arm 3（High-Intensity Interval Training ）
One intervention session scheduled in the afternoon. The protocol consists of 10 sets of 6-second high-knee exercise, separated by 9 seconds of rest between sets.
干预措施: High-Intensity Interval Training (Behavioral)
结局指标
主要结局
Changes in cognitive function assessed by cognitive test battery
时间窗: Baseline and immediately after the acute intervention
Changes in cognitive performance measured after each intervention condition, including attention and executive function.
次要结局
- Prefrontal cortex activation measured by electroencephalography (EEG)(Baseline and immediately after the acute intervention)