Anesthesia With Sevoflurane and Isoflurane for Excision Surgeries in Benign Breast Tumors
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 500
- 试验地点
- 1
- 主要终点
- Time of induction, maintenance and resuscitation
研究概览
简要总结
Generally, benign breast tumors are excised under the local anesthesia. But such action was so invasive that every patient would experience the physiological and psychological stimuli unavoidably. Sevoflurane was advised as a better inhalational anesthesic for its "easy come,easy go" property during short-lasting operations than isoflurane. We purposed that sevoflurane would be a superior anesthesic for benign breast tumor excision than isoflurane with relative less alteration in hemodynamics, less postoperative side effects and easily-control the depth of anesthesia.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 64 Years(Adult)
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Diagnosed benign breast tumor patients
- •18-64 yrs
排除标准
- •Allergic to any interventional drugs
- •Organic dysfunction
- •Long-lasting PACU staying
研究组 & 干预措施
1
Sevoflurane: induction 3-6%, maintenance 2-3%
干预措施: Sevoflurane (Drug)
2
Isoflurane: induction 3-6%, maintenance 2-3%
干预措施: Isoflurane (Drug)
结局指标
主要结局
Time of induction, maintenance and resuscitation
时间窗: 0h to the end of the operation
次要结局
- Intraoperative hemodynamics; Postoperative side effects;(0h to 24h after the end of the operation)
