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临床试验/NCT00575354
NCT00575354已完成4 期

Anesthesia With Sevoflurane and Isoflurane for Excision Surgeries in Benign Breast Tumors

Nanjing Medical University1 个研究点 分布在 1 个国家目标入组 500 人开始时间: 2007年3月最近更新:
适应症
干预措施
相关药物

试验速览

阶段
4 期
状态
已完成
发起方
入组人数
500
试验地点
1
主要终点
Time of induction, maintenance and resuscitation

研究概览

简要总结

Generally, benign breast tumors are excised under the local anesthesia. But such action was so invasive that every patient would experience the physiological and psychological stimuli unavoidably. Sevoflurane was advised as a better inhalational anesthesic for its "easy come,easy go" property during short-lasting operations than isoflurane. We purposed that sevoflurane would be a superior anesthesic for benign breast tumor excision than isoflurane with relative less alteration in hemodynamics, less postoperative side effects and easily-control the depth of anesthesia.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)

入排标准

年龄范围
18 Years 至 64 Years(Adult)
性别
Female
接受健康志愿者

入选标准

  • Diagnosed benign breast tumor patients
  • 18-64 yrs

排除标准

  • Allergic to any interventional drugs
  • Organic dysfunction
  • Long-lasting PACU staying

研究组 & 干预措施

1

Active Comparator

Sevoflurane: induction 3-6%, maintenance 2-3%

干预措施: Sevoflurane (Drug)

2

Active Comparator

Isoflurane: induction 3-6%, maintenance 2-3%

干预措施: Isoflurane (Drug)

结局指标

主要结局

Time of induction, maintenance and resuscitation

时间窗: 0h to the end of the operation

次要结局

  • Intraoperative hemodynamics; Postoperative side effects;(0h to 24h after the end of the operation)

研究者

发起方
Nanjing Medical University
申办方类型
Other

研究点 (1)

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