Continuous Saphenous Nerve Block (Adductor Channel) and Local Infiltration Analgesia (LIA) for Total Knee Arthroplasty
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 40
- 试验地点
- 2
- 主要终点
- Pain scores
研究概览
简要总结
Our study will compare the use of continuous saphenous nerve block performed at the adductor canal in addition to Local Infiltration Analgesia (LIA) versus a Sham block in addition to LIA for total knee replacement. The investigators hypothesize that the saphenous nerve block performed at the level of the adductor canal in addition to LIA provides better pain relief than the LIA alone without significantly compromising muscle strength and physiotherapy, enabling patients to mobilize early with reduced opioid consumption and les side effects.
The investigators will enroll a total of 40 patients (20 patients will receive continuous saphenous nerve block in addition to LIA and 20 will receive the sham block and LIA). Until discharge, the investigators will record patients' pain scores, opioid consumption, side effects and physical therapy progress.
If our study proves that the continuous saphenous nerve block in addition to LIA can effectively reduce postoperative pain scores to an acceptable level with better physical therapy progress and less opioid consumption, it could be seen as a more attractive alternative to LIA alone or other traditionally used methods of postoperative pain control that compromises muscle strength and physiotherapy.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 40 Years 至 75 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •ASA I-III
- •Age: 40-75
- •Unilateral TKA
- •Use of Spinal anesthesia
排除标准
- •Allergy to any of the study medications
- •Intolerance to morphine
- •Contraindication to a spinal anesthetic
- •Intraoperative use of any volatile anesthetic
- •Chronic opioid use
- •ASA Class 4-5
- •Rheumatoid arthritis or Diabetes mellitus with neuropathy
- •Liver or kidney failure
- •BMI above 40
- •Severe COPD
结局指标
主要结局
Pain scores
时间窗: 3 days postoperative
VAS pain scores
次要结局
- physical therapy progress(3 days postoperative)
- Opioid consumption(3 days postoperative)
研究者
Henning Lykke Andersen
Consultant
Frederiksberg University Hospital
