ACTRN12624001179527招募中Unknown
Genicular Artery Embolisation (GAE) in Mild to Moderate Osteoarthritis: Correlation between Treatment Effect and Biochemical Biomarkers
I-MED Radiology Network0 个研究点目标入组 70 人开始时间: 2024年9月25日最近更新:
适应症
试验速览
- 阶段
- Unknown
- 状态
- 招募中
- 发起方
- 入组人数
- 70
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 40 Years 至 No limit（—）
- 性别
- All
入选标准
- •Participants deemed suitable for recruitment into the PRAETORIAN registry will be invited to decide if they would also like to participate in the sub-study. The inclusion and exclusion criteria for the PRAETORIAN registry are as follows, and there are no additional criteria for inclusion in this sub-study beyond those listed for the PRAETORIAN registry. Inclusion criteria for group A (patients with moderate-to-severe chronic pain following Total Knee Arthroplasty (TKA)):- Age 40 yrs or older who are willing and able to provide informed consent- Experiencing ongoing moderate to severe pain for at least 6 months after total knee arthroplasty- and having failed conservative medical treatment for at least 6 months (e.g. physiotherapy/anti-inflammatory/analgesia/masso-kinesiotherapy, etc.)Inclusion criteria for group B (patients with mild-to-severe Knee Osteoarthritis (KOA)):- Age 40 yrs or older who are willing and able to provide informed consent- Presence of mild to severe knee OA as stipulated by referring orthopedic surgeon- Presence of knee pain for at least 6 months, resistant to conservative treatments (e.g. physiotherapy, analgesia, exercise, weight loss, intra-articular injections, etc.)- Non-surgical candidates: ineligible/refused total knee arthroplasty (TKA)
排除标准
- •The exclusion criteria are the same as those for the PRAETORIAN registry, with no additional exclusion criteria for this sub-study. The exclusion criteria are as follows: Exclusion criteria for group A (patients with moderate-to-severe chronic pain following Total Knee Arthroplasty (TKA)):- Rheumatoid, infectious arthritis, osteonecrosis, or advanced atherosclerosis- Malignancy- Renal impairment (eGFR <45)- A bleeding diathesis- Irreversible coagulopathy- Re-operation- Allergic to contrast mediaExclusion criteria for group B (patients with mild-to-severe Knee Osteoarthritis (KOA)):- Rheumatoid, infectious arthritis, osteonecrosis, or advanced atherosclerosis- Malignancy- Renal impairment (eGFR <45)- A bleeding diathesis- Irreversible coagulopathy- Allergic to contrast media
研究者
相似试验
进行中（未招募）
Unknown
Genicular artery embolisation for osteoarthritis of the knee in WalesTreatment of pain associated with osteoarthritis of the kneeMusculoskeletal DiseasesISRCTN82978621Aneurin Bevan University Health Board31
尚未招募
不适用
Genicular artery embolisation and the effect on Knee Osteoarthritis - a randomised controlled trial.Musculoskeletal - OsteoarthritisKnee osteoarthritisACTRN12622001157763South Western Sydney Local health District54
尚未招募
不适用
A clinical trial to study the effects of genicular artery embolization, in which the blood vessels supplying the diseased knee are blocked using a minimally invasive angiography-based technique, and compare it with standard therapy, in the patients suffering from osteoarthritis of the kneeCTRI/2022/09/045508All India Institute of Medical Sciences Patna
进行中（未招募）
不适用
Genicular Artery Embolization Vs Observation for Symptomatic Knee OsteoarthritisDegenerative Joint Disease of KneeKnee OsteoarthritisNCT04682652University of California, Los Angeles100
撤回
不适用
Genicular Artery Embolization (GAE) for the Treatment of Chronic Post Knee Arthroplasty PainKnee Pain ChronicKnee Swelling PainArterial OcclusionNCT05248308Brigham and Women's Hospital