JPRN-UMIN000020894进行中（未招募）未知
Effect of supplement involved ferulic acid, glycerophosphocholine and ginkgo leaf extract on mild cognitive impairment. -A randomized, double-blind, placebo-controlled, parallel-group clinical trial
FANCL Corporation Research Institute0 个研究点目标入组 60 人开始时间: 2016年2月5日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 60
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 65years-old 至 ot applicable（—）
- 性别
- All
入选标准
- •1 Subjects with MCI and who meet the following criteria
- •Amnestic MCI
- •CDR 0 or 0.5
- •MMSE 22-26 and/or ADAS-jcog 5-15
- •2 Subjects who giving written informed consent
排除标准
- •1) Subjects who use or plan to use go drugs affecting cognitive function or dementia.
- •2) Subjects who constantly use Kampo preparation affecting cognitive function or dementia.
- •3) Subjects who constantly use functional supplement affecting cognitive function or dementia.
- •4) Subjects who have psychiatric disorder (schizophrenia, mania, depression, severe cardiopathy, delirium, alcoholism etc.) affecting cognitive function or dementia with the exception of complete remission.
- •5) Subjects who take medical treatment for psychoneurosis (confusion, hallucination, delusion, abnormal behavior etc.) with antipsychotic drug.
- •6) Subjects with metabolic disease (hypothyroidism, deficiency of vitamin B12, etc.) affecting cognitive function or dementia.
- •7) Subjects with liver disease, renal disease or hypoactivity of renal function (eGFR<=20 mL/min).
- •8) Subjects with type 2 diabetes and HbA1c>8.4%, insulin treatment or taking drug for insulin secretion accelerating agent.
- •9) Subjects with chronic obstructive lung disease (COPD) and oxygen therapy in home or FEV1<30%.
- •10) Subjects with essential hypertension or uncontrolled hyperlipidemia.
- •11) Subjects who have medical history of gastrointestinal surgery or hospitalization for head injury within 10 years.
- •12) Subjects who have history of intracerebral hemorrhage, subarachnoid hemorrhage, cardiac hypertrophy?cardiac failure, ischemic heart disease(IHD), nephrosclerosis, aortic dissection, cerebral infarction.
- •13) Subjects who take medical treatment for cancer.
- •14) Subjects who are planned to participate in other clinical study.
- •15) Subjects who are judged as unsuitable for the study by the investigator for other reason.
研究者
相似试验
已完成
不适用
Effect of supplement involved ferulic acid, glycerophosphocholine, ginkgo leaf extract and vitamin C on mild cognitive impairment. -Before after studyMild Cognitive ImpairmentJPRN-UMIN000036381FANCL Corporation40
已完成
3 期
Effect of Fenugreek Seed Extract on inflammation in Patients with Type 2 DiabetesType 2 Diabetes.Type 2 diabetes mellitusIRCT20210407050880N1Tabriz University of Medical Sciences46
已完成
3 期
Effect of fenugreek seed extract on oxidative stress in type 2 diabetic patientsIRCT20210407050881N1Tabriz University of Medical Sciences46
招募中
Unknown
The efficacy of ferulic acid and Angelica archangelica extract on patients with mild Alzheimer's dementiaAlzheimer's dementiaAlzheimer's disease dementiaD000544JPRN-jRCTs031220615So Mirai320
已完成
不适用
The efficacy of ferulic acid in the treatment of dementiaJPRN-UMIN000003683Shimane University Hospital50