Mise au Point de Protocoles RMN Sur l'Imageur Philips 3T installé Sur le Site du Pavillon Baudot du CHU Purpan à Toulouse
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 230
- 试验地点
- 1
- 主要终点
- quality of MRI images
研究概览
简要总结
Since January 2010, a new magnetic resonance imaging scanner (Philips 3T, Achieva) is installed on the Baudot Building in Toulouse hospital. This tool, is completely dedicated to the research. It was installed with sequences RMN supplied by the manufacturer.
Imagers also contain an instrumentation susceptible to evolution and/or to adjustment (antennas radio frequency, sheath of gradients, elements of physiological monitoring (for example control of the breath), regulation of the homogeneity of the magnetic field).
This MRI scanner and this instrumentation are used for anatomical examinations or for paradigms of cognitiveresearch (for example of detection of intellectual activations following simple stimuli of fingers movement, visual tasks, or of mental processes).
The developpement of this equipment is going to favor the emergence of numerous projects and new themes, up to there adressed by other techniques (psychophysics, EEG).
To obtain good quality signals and know the practical limits of this imager, it is thus necessary that the researchers doctors, physicists and engineers, can finalize on volunteers' significant number, all the sequences RMN necessary for the use of these tools for the research.
These developments are going to get organized around four main axes:
1 the control of the geometrical distortions (generated by the introduction of an object within the magnetic field) 2 Optimization of the parameters of sequences to improve the contrast and the spatial resolution of the obtained images 3 the development of new sequences 4 the feasibility study of the protocols of functional MRI
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Healthy adult, age = 18 years;
- •Visual, hearing , oral or written capacities and expression sufficient for the suitable realization of the tests;
- •Obtaining of the informed consent of the subject.
排除标准
- •Subjects presenting a neurological, psychiatric history;
- •Subjects under chronic medication which can influence the intellectual activity;
- •Subjects presenting a contraindication to the MRI (carriers of a pacemaker, an implanted material(equipment) activated by an electric, magnetic or mechanical system, carriers of haemostatic clips of anévrysmes intracérébraux or carotid arteries, carriers of orthopaedic, claustrophobic implants);
- •Subjects refusing to be informed about the possible presence of an anatomical anormality;
- •administrative Problems: impossibility to give about the information, no insurance, refusal to sign the consent, under guardianship subject ;
- •Subjects participating in another protocol • pregnancy
研究组 & 干预措施
control
MRI exam; The sequences to be performed will be presented to the subject according to the focus to be performed. maximal duration of the exam: 2 hours (including subject set up)
干预措施: mri (Other)
结局指标
主要结局
quality of MRI images
时间窗: 90 months
assessment of distortion of MRI images
Assessment of distortion of MRI images
时间窗: 90 months
Measurement of contrasts of MRI sequence
时间窗: 90 months
By using available software such as MRICro, Image J, Matlab or other post-processing tools developed as required
Measurement of MRI sequence resolution
时间窗: 90 months
To estimate the resolution by measuring the signal-to-noise ratio using standard software such as MRICro, Image J, Matlab or other post-processing tools developed as required
次要结局
未报告次要终点