The Effects of Dexamethasone and Ibuprofen on Postoperative Analgesia in Patients Undergoing Hand and Forearm Surgery With Axillary Brachial Plexus Block
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 79
- 试验地点
- 1
- 主要终点
- Duration of analgesia
研究概览
简要总结
This study aims to comparatively examine the effects of preemptive intravenous dexamethasone and intravenous ibuprofen use on the duration of analgesia in ultrasound-guided Axillary Brachial Plexus Block applications for patients undergoing hand and forearm surgery. Furthermore, investigating the relationship between the study drugs and the incidence of Postoperative Nausea and Vomiting and determining the time until the first use of rescue analgesic are also among the secondary objectives.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patient's consent to participate in the study (Informed consent)
- •Aged between 18 and 65 years
- •ASA physical status I or II
- •Being oriented and cooperative
- •Scheduled to undergo hand or forearm surgery
- •Body Mass Index (BMI) below 40 kg/m²
- •Scheduled for axillary brachial plexus blockade
排除标准
- •Patient's refusal to participate in the study
- •Refusal of regional anesthesia
- •Known allergy to local anesthetics
- •Known allergy to ibuprofen
- •Known allergy to dexamethasone
- •Presence of coagulopathy
- •Local infection at the site of regional anesthesia application
- •Presence of malignancy at the surgical site
- •Diagnosis of diabetes mellitus
- •Body Mass Index (BMI) of 40 kg/m² or above
- •Duration of surgery exceeding 4 hours
- •Administration of opioid medication during the preoperative or intraoperative period
研究组 & 干预措施
D
Patients who had intravenouse dexamethasone
干预措施: IV Dexamethasone 8mg (Drug)
I
Patients who had intravenouse ibuprofen
干预措施: iv ibuprofen (Drug)
结局指标
主要结局
Duration of analgesia
时间窗: 24 hours
Duration of analgesia was defined as the time from the performance of the block until the patient's first report of pain.
次要结局
- Incidence of PONV(24 hours)
研究者
Ayşegül Bilen
Associate Professor
Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization