Prospective Registry of Outcomes and Management of Acute Ischaemic Syndromes
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 1,340
- 试验地点
- 38
- 主要终点
- Adherence to the educational programme measured by the frequency of use of the evidence based treatments: Aspirin, Heparin, Clopidogrel, Beta blockers, Statins.
研究概览
简要总结
This is a multi-centre UK study designed to evaluate if an educational intervention programme delivered to health care professionals can improve the use of evidence based treatments in the management of patients admitted to hospital with non-ST elevation Acute Coronary Syndrome. A total of 38 centres participated, half received the educational intervention. Patients were followed to hospital discharge. Patients were followed up at 6 months. Longer term follow up through the Office Of National Statistics will be performed.
详细描述
This is a multi-centre UK study designed to evaluate if an educational intervention programme delivered to health care professionals can improve the use of evidence based treatments in the management of patients admitted to hospital with non-ST elevation Acute Coronary Syndrome. A total of 38 centres participated. A cluster randomised method was used and half of centres received the educational intervention. Patients were followed to hospital discharge. Patients were followed up at 6 months and longer term follow up for mortality will be performed through the national databases.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Health Services Research
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All patients admitted to the hospital (either through casualty or directly to the wards), with a good clinical history of an acute coronary syndrome with one or more of the following:
- •Ischaemic changes on the admission ECG (including patients with bundle branch block)
- •Elevated Troponin or cardiac enzymes on admission
- •Normal ECGs but with evidence of pre-existing coronary artery disease i.e., evidence of a prior history of MI, coronary revascularisation, coronary angiography demonstrating the presence of significant coronary stenosis or a stress test demonstrating ischaemia (treadmill, echo or nuclear scan)
- •Written informed consent
排除标准
- •Patients with persistent ST elevation >1mm in two or more contiguous leads on the ECG.
- •Patients treated with thrombolytic therapy, or for whom thrombolytic therapy was considered on admission.
结局指标
主要结局
Adherence to the educational programme measured by the frequency of use of the evidence based treatments: Aspirin, Heparin, Clopidogrel, Beta blockers, Statins.
次要结局
- Comparison of investigations and tests
- Use of other treatments
- Counselling for lifestyle changes
- Referral to smoking cessation clinics
- Cardiac rehabilitation
- Compliance to treatment at 6 months
- Comparison of clinical events at 6 months