Effectiveness of Pumpkin Seed Extract on Improving Blood Sugar Level in Subhealth Subjects
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 60
- 试验地点
- 2
- 主要终点
- Biochemical analysis
研究概览
简要总结
This randomized, double-blind, placebo-controlled, and parallel clinical study aims to investigate the effectivness of a pumpkin seed extract on blood sugar management in subhealth people.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 20 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Fasting blood sugar levels from 100 to 125 mg/dL
- •Glycated hemoglobin levels from 5.7 to 6.4%
- •2-hour OGTT levels from 140 to 199 mg/dL
排除标准
- •Pregnant women or preparing for pregnancy.
- •Lactating women.
- •Women gave birth 6 months before the study.
- •Poor kindy funciton
- •Severe cardiovascular or other chronic diseases
- •Patients with type I or II diabetes
- •Poor compliance
- •Alcohol abuser
- •Using anti-diabetic or weight managent supplements
- •Blood transfusion three months before the study
- •Pumpkin seed allergy
研究组 & 干预措施
Placebo group
Placebo capsule, one capsule/day (300 mg/day) for 3 months
干预措施: Placebo (Dietary Supplement)
Low dose
Pumpkin seed extract capsule, one capsule/day (300 mg/day) for 3 months
干预措施: Pumpkin seed extract (Low dose) (Dietary Supplement)
High dose
Pumpkin seed extract capsule, two capsules/day (600 mg/day) for 3 months
干预措施: Pumpkin seed extract (High dose) (Dietary Supplement)
结局指标
主要结局
Biochemical analysis
时间窗: Baseline up to 12 weeks
Changes in fasting blodd sugar levels of 60 pariticpants will be analyzed between baseline and week 12.
Hormone analysis
时间窗: Baseline up to 12 weeks
Changes in GLP-1 levels of 60 pariticpants will be analyzed between baseline and week 12.
次要结局
未报告次要终点