Early Goal Directed Therapy in Sepsis by EMS
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 试验地点
- 2
- 主要终点
- Time to antibiotics
研究概览
简要总结
The goal is to evaluate the best way for paramedics and hospitals to work together to treat septic patients as quickly as possible.
The investigators think that the best thing to do for septic patients is to identify and treat them as early as possible. This research will test this. The investigators think that if paramedics identify septic patients and begin treatment with fluids in the ambulance, then the patient will do better in the long run. The paramedic will also tell the hospital that a septic patient will be there soon. The caregivers can prepare and be ready to provide care as soon as the patient arrives. With this research, the investigators would like to see if these steps help patient outcomes.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 17 Years 至 —（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Older than 17 years of age
- •Suspected to having an infection
- •Meets 2 of 3 systemic inflammatory response criteria: heart rate > 90 beats per minute, respiratory rate >20 breaths per minute, temperature >38°C or <36°C
排除标准
- •Transfer from another hospital
- •Patients, coming from a rehabilitation/nursing facility where antibiotics were given prior to transfer
- •Pregnant patients
- •Prisoners.
结局指标
主要结局
Time to antibiotics
时间窗: During the Emergency Department stay (expected to be 5 hours)
次要结局
- Mortality(Participants will be followed for the duration of hospital stay, an expected average of 1 week)
- Admitted to the Intensive Care Unit from the Emergency Department(During the Emergency Department stay (expected to be 5 hours))
- Need for pressors in the Emergency Department(During the Emergency Department stay (expected to be 5 hours))
研究者
Michael Filbin, MD
Principal Investigator
Massachusetts General Hospital