Transcranial direct current stimulation and exposure and response prevention for treatment resistant obsessive-compulsive disorder: A case series

Curtin University Western Australia0 个研究点目标入组 7 人开始时间: 2021年1月18日最近更新: 2023年6月5日

适应症

试验速览

暂无简介。

•A clinical diagnosis of DSM-5 OCD using the MINI International Neuropsychiatric Interview.
•Treatment Refractory, defined as a Yale-Brown Obsessive Compulsive Scale total score of > 16 (moderate to extreme) after two failed pharmacological treatments for OCD, and unsuccessful cognitive behaviour therapy with exposure and response prevention.

•1. Participants with a recent history of brain surgery, neurological condition associated with brain abnormalities (e.g., traumatic brain injury; recent stroke, tumour), implanted cranial devices, hearing aids (unless they can be removed), active skin lesions on the scalp.
•2. History of migraine, epilepsy, seizures, unstable medical and/or psychiatric conditions; history of psychosis or bipolar disorder; high suicide/self-harm risk.
•3. Current or past (within the last 1-month) use of benzodiazepines, anticonvulsants, Lithium Carbonate, psychostimulants, dextromethorphan and pseudoephedrine; recreational drug use.
•4. Currently undergoing ERP therapy for OCD; any neuromodulation therapy (e.g., ECT, transcranial magnetic stimulation, tDCS) within the last 3-months.
•5. Participants who have initiated or changed SSRI/SRI dose in the last 12 weeks.

发起方

Curtin University Western Australia