The Effect of Whole Body Vibration Training on Pulmonary Rehabilitation in Patients With Chronic Obstructive Pulmonary Disease
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 26
- 试验地点
- 1
- 主要终点
- FVC(% pred)
研究概览
简要总结
Although whole body vibration (WBV) is mainly designed to promote neuromuscular function, however, because of its vibration characteristics, whether it can provide additional effects on the sputum clearance for chronic obstructive pulmonary (COPD) disease patients, thereby improving the quality of life, and exercise capacity is still unknown.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 35 Years 至 90 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Confirmed diagnosis of COPD at the outpatient thoracic medicine clinic
- •Need HFCWO as judged by the doctor
排除标准
- •Acute COPD exacerbation within the previous 4 weeks,
- •Contraindication for WBVT (e.g., artificial joint replacement, a history of deep vein thrombosis, or known aortic aneurysm)
- •Inability to perform squatting exercises
- •Acute disc disease
- •Inability to complete the 6MWT
研究组 & 干预措施
HFCWO+WBVT
Subjects received HFCWO+WBVT intervention twice a week for a period of 8 weeks
干预措施: A vertical vibration platform PowerVibe Zen Pro 5900 (Device)
HFCWO+WBVT
Subjects received HFCWO+WBVT intervention twice a week for a period of 8 weeks
干预措施: HFCWO (Device)
HFCWO only
Subjects received HFCWO intervention twice a week for a period of 8 weeks
干预措施: HFCWO (Device)
结局指标
主要结局
FVC(% pred)
时间窗: 8 weeks
percentage of predicted FVC value (% pred)
chronic obstructive pulmonary disease assessment test (CAT)
时间窗: 8 weeks
questionnaire of COPD symptoms, scores ranging from 0 to 40, higher scores indicating more severe impact of COPD on their life
1 min STST
时间窗: 8 weeks
the number of repetitions performed in the 1-min sit-to-stand test (rep.)
FVC
时间窗: 8 weeks
forced vital capacity tested in pulmonary function test (Liters)
Distance-Saturation Product (DSP)
时间窗: 8 weeks
the product of distance walked and lowest oxygen saturation during the 6-min walk test (m%)
FEV1/FVC
时间窗: 8 weeks
forced expiratory volume in 1 second divided by forced vital capacity in pulmonary function test (%)
Predicted distance
时间窗: 8 weeks
percentage of the predicted 6 minute walk test distance (%pred)
5-rep STST
时间窗: 8 weeks
the complete time for the 5-repetition sit-to-stand test (sec)
Muscle strength test2
时间窗: 8 weeks
maximal force output for quadriceps muscle (lbs)
X-ray score
时间窗: 8 weeks
the evaluation of the chest radiography based on the sputum impaction score, scores ranging from 0 to 18. A decrease in score represented an improvement in sputum in each area.
modified Medical Research Council (mMRC)
时间窗: 8 weeks
questionnaire of dyspnea, scores ranging from 0 (low degree of dyspnea) to 4 (high degree of dyspnea)
Saint George Respiratory Questionnaire (SGRQ)
时间窗: 8 weeks
questionnaire of overall health, daily life, and perceived well-being, scores ranging from 0 (no health impairment) to 100 (maximum health impairment)
FEV1
时间窗: 8 weeks
forced expiratory volume in 1 second in pulmonary function test (Liters)
FEV1(% pred)
时间窗: 8 weeks
percentage of predicted FEV1 value (% pred)
6 min walk distance
时间窗: 8 weeks
the distance walked in 6 minutes (m)
Muscle strength test1
时间窗: 8 weeks
Maximal force output for biceps femoris muscle (lbs)
Sputum self-assessment scale
时间窗: 8 weeks
questionnaire of sputum volume, it contained three items (0-25 mL/d, 25-50 mL/d, and 50-100 mL/d) as a checklist
次要结局
未报告次要终点