Standardized dietary challenges in healthy and diabetic subjects - Standardized dietary challenge study

TNO0 个研究点目标入组 40 人开始时间: 待定最近更新: 2024年4月29日

适应症

试验速览

暂无简介。

•Males, aged 30 to 55 years.
•20 healthy volunteers are defined based on 1) Medical history evaluation; 2) Physical examination; 3) results of the prestudy laboratory tests; 4) Body mass index (BMI): 20-25 kg/m2.
•20 Type 2 Diabetes, BMI: 25.1-30 kg/m2, willing to stop antidiabetic medication.

•1)Uncontrolled bloodpresseure: systolic blood pressure >= 150 mmHg; diastolic blood pressure >= 95mmHg.
•2)Use of medication that might interfere with parameters to be measured with one of the challenge tests, with the exception of oral antidiabetic drugs. ( use beta blockers, statins, antidiabetic drugs during the study).
•4)physical activity (more than 6 hours per week)
•5)unexplained weight loss or gain of > 4 kg in the month prior to the screening
•6)followed slimming or medically prescribed diet
•7) food allergy or sensitivity
•8) For diabetic subjects, fasting glucose < 10mmol/L after stopping metformin for one week.

发起方

TNO