Pilot Study: 3-D Reconstruction of CT Scan Images in the Evaluation of Non-Specific Pulmonary Nodules
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 19
- 试验地点
- 1
- 主要终点
- To collect preliminary data regarding the comparative sensitivity and specificity of conventional CT scan and three-dimensional CT for detecting the growth of nonspecific pulmonary nodules.
研究概览
简要总结
In recent years, more and more people are having lung CT scans performed to screen for various cancers. Many of them have small abnormalities detected, called "nodules", which - for a variety of reasons - doctors are unable to biopsy. As a result, many patients have their CT scans repeated on a regular basis to see if their nodules grow. This process can last several years.
Many patients experience significant anxiety during this process, when they are aware of a spot in the lung, but are not told any specific cause.
Researchers at Memorial Sloan-Kettering have developed a new way to look at lung nodules in three dimensions. The purpose of this project is to see if any change in the nodules can be detected sooner by this method than by traditional CT scans.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Referral to the pulmonary or thoracic surgery service for undiagnosed pulmonary nodules.
- •History of smoking exceeding 10 pack-years (pack year defined as number of packs of cigarettes per day multiplied by the number of years smoked).
- •Nodule size 5 to 15 mm in diameter.
排除标准
- •Clinical indication for immediate biopsy via bronchoscopy, fine needle aspiration, or video-assisted thoracoscopic Surgery (VATS)
- •Active lung cancer or metastasis to the lung.
- •Contraindication to needle biopsy.
- •Pneumonectomy
- •Need for supplemental oxygen.
- •Radiation pneumonitis
- •Interstitial lung disease.
结局指标
主要结局
To collect preliminary data regarding the comparative sensitivity and specificity of conventional CT scan and three-dimensional CT for detecting the growth of nonspecific pulmonary nodules.
时间窗: conclusion of the study
次要结局
- To determine three-dimensional characteristics of pulmonary nodules which may discriminate between benign and malignant diseases.(conclusion of the study)