Study of Lipid Profile in Diabetic and Non Diabetic Chronic Kidney Disease Patients in Sohag University Hospital
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- Assessment and comparison of the lipid profile between diabetic and non-diabetic chronic kidney disease patients using the colorimetric method on a fully automated biochemistry analyser.
研究概览
简要总结
The goal of this observational study is to compare blood lipid (fat) levels in participants with chronic kidney disease (CKD) with diabetes and without diabetes and who over 20 years old.
The main question this study aims to answer is:
Does having diabetes make fat problems worse in people with chronic kidney disease (CKD), or is there no connection between them?
Researchers will compare the blood lipid (fat) levels in people with chronic kidney disease (CKD) who have diabetes and those without diabetes to see if having diabetes makes lipid problems worse in CKD patients, or if there is no connection between diabetes and changes in lipid levels.
Participants will need to fast for 10 hours before undergoing this test. This means not eating any food or drinking anything except water.
Samples will be taken and sent to laboratory immediately.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 21 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients of chronic kidney disease (CKD) presenting to the Sohag University Hospital
- •Patients aged above 20 years of age.
- •All patients who have given consent for enrolling into the study.
排除标准
- •Patients aged 20 years of age or below.
- •Patients on lipid-lowering drugs.
- •Kidney transplanted patients.
研究组 & 干预措施
Non-diabetic CKD patients
participants aged over 20 years who have been diagnosed with chronic kidney disease (CKD) but do not have a current or past diagnosis of diabetes mellitus.
Diabetic CKD patients
This group includes participants aged over 20 years who have been diagnosed with both chronic kidney disease (CKD) and diabetes mellitus.
结局指标
主要结局
Assessment and comparison of the lipid profile between diabetic and non-diabetic chronic kidney disease patients using the colorimetric method on a fully automated biochemistry analyser.
时间窗: January 2025 to January 2026.
Lipid profile were assessed in samples of chronic kidney disease patients , both with diabetes and without diabetes, after obtaining informed consent to compare lipid profile between these two groups. Overnight fasting samples were taken and sent to the laboratory immediately. Serum was separated within 2 hours after collection to prevent artifactual changes in the concentration of HDL. After clot retraction occurred, the serum was transferred to a centrifuge tube and centrifuged at 2000 rpm for 5 minutes. The clear supernatant serum was then pipetted out using dry piston pipettes with disposable tips and stored in dry thin walled vials at 4°C. The samples were analyzed on the same day. The following parameters were analyzed using the colorimetric method on a fully automated biochemistry analyser. 1. Serum Cholesterol 2. Serum Triglyceride 3. Serum HDL (high-density lipoprotein) 4. Serum LDL ( low-density lipoprotein) 5. Serum VLDL (very low-density lipoprotein)
次要结局
未报告次要终点
研究者
Shaimaa Mahmoud Elsayed Abdel-Raheem
Principal investigator resident at the Internal Medicine Department, Sohag University Hospital
Sohag University