EUCTR2011-002603-15-ES进行中（未招募）不适用
Early treatment with ganciclovir of active infection by cytomegalovirus (CMV) in critically ill patients on mechanical ventilation with severe sepsis or septic shock
FUNDACION INVESTIGACION HOSPITAL CLINICO DE VALENCIA-INSTITUTO DE INVESTIGACION SANITARIA INCLIVA0 个研究点开始时间: 2011年9月28日最近更新:
适应症
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 发起方
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •? Signing the informed consent (patient or family)
- •? Age equal or greater than 18 years
- •? Positive serology for CMV (IgG and/or IgM) at the time of admission
- •? active CMV infection during their ICU stay (> 10 CMV DNA copies/ml of tracheal aspirate and/or peripheral blood).
- •? Severe sepsis or septic shock (it will follow the definitions of the consensus conference) requiring mechanical ventilation.
- •? Women of childbearing potential must test negative serum or urine test and use effective contraception.
- •? Admitted to ICU
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range 42
- •F.1.3 Elderly (>=65 years) yes
- •F.1.3.1 Number of subjects for this age range 42
排除标准
- •? Patients who are participating in other clinical trials.
- •? Immunosuppression known at the time of admission
- •? Neutropenia (neutrophils <500/?l)
- •? Thrombocytopenia (<25x10^9/L)
- •? Liver failure: bilirubin>2 mg/dL
- •? Patients who are pregnant or breastfeeding.
- •? Other contraindications listed in the Summary of ganciclovir
研究者
相似试验
进行中（未招募）
不适用
PTH study: Preemptive Treatment for Herpesviridaemechanically ventilated patientsEUCTR2012-003312-30-FRASSISTANCE PUBLIQUE HOPITAUX DE MARSEILLE
已完成
4 期
PTH - Preemptive Treatment for HerpesviridaeViral PneumoniaNCT02152358Assistance Publique Hopitaux De Marseille317
已完成
2 期
Ganciclovir by Infusion and by Mouth in Treating Patients With Cytomegalovirus After Donor Bone Marrow TransplantMyelodysplastic/Myeloproliferative Neoplasm, UnclassifiableMDSMyelodysplastic/Myeloproliferative DiseasesMultiple MyelomaLymphomaLeukemiaNCT00530218City of Hope Medical Center61
未知
不适用
Effectiveness and satety,topical ganciclovir case of cytomegalovirus corneal endotheliitisJPRN-UMIN000026809Toho university20
已完成
2 期
role of ganciclovir in the prevention of Post-transplant lymph proliferative disease in children underwent liver transplantatioTransplanted organ and tissue status.Liver transplant statusIRCT2013120215530N2Vice Chancellor for research,Shiraz University of Medical Sciences203