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临床试验/CTRI/2025/05/086932
CTRI/2025/05/086932尚未招募2/3 期

A Comparative Clinical Study To Evaluate The Analgesic Effect Of Polyherbal Formulation Sachet And Diclofenac Sachet In Dantashool W.S.R. To Toothache.

Parul Institute Of Ayurveda And Research1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2025年1月7日最近更新:

试验速览

阶段
2/3 期
状态
尚未招募
发起方
入组人数
60
试验地点
1
主要终点
Reduces the severity of toothache.

研究概览

简要总结

Toothache, known as Dantashool in Ayurveda, is a common dental condition that presents significant challenges due to its diverse causes and debilitating symptoms. Traditional management primarily utilizes pharmacological interventions, particularly non-steroidal anti-inflammatory drugs (NSAIDs) such as diclofenac, which alleviate pain through the inhibition of prostaglandin synthesis. However, concerns regarding their adverse effects, including gastrointestinal and cardiovascular risks, underscore the need for safer alternatives. This study aims to conduct a comparative clinical evaluation of the analgesic efficacy and safety of a polyherbal formulation sachet versus diclofenac sachet in managing toothache. By analyzing the effectiveness, tolerability, and adverse reactions of these two interventions, this research seeks to provide insights into the potential of polyherbal formulations as a viable alternative for pain management in dental practice. The implications of this study could enhance the quality of dental care by optimizing pain relief while minimizing risks associated with conventional NSAIDs, ultimately contributing to improved oral health outcomes for individuals suffering from toothache.

研究设计

研究类型
Interventional
分配方式
Computer generated randomization
盲法
Open Label

入排标准

年龄范围
18.00 Year(s) 至 60.00 Year(s)(—)
性别
All

入选标准

  • The Patients Who Are Diagnosed On The Basis Of Signs And Symptoms Of Dantshool.

排除标准

  • Age: Below 18 years And above 60 years.
  • Fractured tooth.
  • Patients with periodontal abscess.
  • Patients with other diseases of oral cavity.
  • CHD Patients.

结局指标

主要结局

Reduces the severity of toothache.

时间窗: at baseline.

次要结局

  • Improvement in Toothache Severity, Quality of Life, Changes in Sleep Quality, etc.(at baseline.)

研究者

发起方
Parul Institute Of Ayurveda And Research
申办方类型
Research institution and hospital

研究点 (1)

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