NCT01084226已完成2 期
Dietary Intervention Trial of Alkylresorcinols and Plant Sterols in High-Fibre Rye Bread and Their Effects on Serum Lipids in Normo- and Mildly Hypercholesterolemic Subjects
适应症
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 入组人数
- 68
- 试验地点
- 2
研究概览
简要总结
The purpose of this study is to investigate the antioxidative effects of alkylresorcinols (AR), originating from the rye fiber, on serum LDL particles and the use of AR or it's metabolites as biomarkers for rye fiber intake and the effect of additional plants sterols, incorporated in the rye bread, on serum total and LDL cholesterol concentration.
研究设计
- 研究类型
- Interventional
- 干预模型
- Parallel
- 盲法
- Triple (Participant, Care Provider, Investigator)
入排标准
- 年龄范围
- 20 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •volunteer
- •hemoglobin above 125 mmol/L in females, above 135 mmol/L in males
排除标准
- •taking drugs affecting plasma lipids or gastrointestinal track
- •severe illness
- •use of antibiotics within 3 months before entering the study
- •use of vitamin pills or fish oil 1 month before entering the study
- •pregnancy or lactating
研究者
研究点 (2)
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