跳至主要内容
临床试验/NCT05622149
NCT05622149已完成不适用

Is Strength Training a Viable Exercise Modality for Fat Loss?

George Washington University0 个研究点目标入组 40 人开始时间: 2016年3月18日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
40
主要终点
Change in Fat Free Mass

研究概览

简要总结

The purpose of this study is to determine whether strength training can be used as a viable exercise modality for the purpose of inducing fat loss.

详细描述

Aerobic exercise (AE) is commonly recommended as the most effective exercise modality for weight loss. The Centers for Disease Control (CDC) recommends 150 minutes of AE for weight maintenance, and an unspecified greater amount required for weight loss. Similarly, the American College of Sports Medicine (ACSM) position stand on physical activity for weight loss recommends 150-250 minutes per week of moderate intensity physical activity. While the ACSM promotes resistance training (RT) as a means of increasing fat free mass, which should lead to improved body composition, it does not promote RT for losing significant amounts of body fat. Similarly, the CDC physical activity guidelines for weight loss do not mention RT at all as a viable exercise modality for weight loss. This is not surprising, as there is a paucity of research examining the effects of RT on weight loss. Furthermore, the few studies that have explored RT for weight loss generally show that it is ineffective. The effectiveness of any weight loss program is dependent on the size of the caloric deficit that is created over time, and since AE generally burns more calories per unit of time than RT, it stands to reason that AE would be the most commonly prescribed type of exercise for weight loss. Contributing to the exclusion of RT for weight loss is a widespread belief among dietitians, nutritionists and exercise professionals that it is not possible to induce muscle growth while in a caloric deficit, and since the creation of a caloric deficit is essential for fat loss, the use of RT for muscle growth in a caloric deficit is counter intuitive.

However, RT has been shown to elevate resting metabolism for an extended period of time following cessation of the training session. Additionally, having a greater muscle mass should lead to a greater resting metabolism. Unlike RT, chronic AE performed in a caloric deficit (which is often the recommendation for effective weight loss) has the potential to lead to significant decreases in muscle mass, thereby hampering improvements in body composition. Ideally, a program designed to improve body composition should do so through fat losses alone, with muscle mass being maintained or increased.

Several reasons could exist for the lack of effectiveness of RT shown in most studies. These reasons include, but are not limited to, 1) Body mass being the measured outcome and not body composition, 2) lack of control and/or measurement of caloric intake, 3) failure to adjust dietary protein needs to support muscle growth, 4) ineffective RT program design. Case studies of clients from our lab have routinely shown that profound decreases in bodyfat can be induced with RT as the exclusive form of exercise. Furthermore, these decreases in bodyfat occur with concomitant increases in muscle mass, while in a caloric deficit. Therefore, the specific aims of this proposal are:

  1. To determine whether RT combined with dietary intervention (RT+DIET) results in greater decreases in fat mass than (RT) or dietary intervention (DIET) alone.
  2. To determine whether RT combined with dietary intervention (RT+DIET) results in greater improvements in body composition than (RT) or dietary intervention (DIET) alone.
  3. To determine whether concomitant increases in muscle mass and decreases in fat mass can occur while in a caloric deficit.

The goal of this project is to serve to generate pilot data to determine whether RT can be used as a viable exercise mode for fat loss and muscle gain. We will then pursue funding for a subsequent study that compares the effects of RT versus AE on body composition and fat loss when 1) the caloric intake is monitored to ensure the creation of a caloric deficit, and 2) dietary protein is appropriately increased to support muscle retention/growth.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
None

入排标准

年龄范围
25 Years 至 40 Years(Adult)
性别
Female
接受健康志愿者
是

入选标准

  • •BMI 25-29.9 normally menstruating bodyfat >30%

排除标准

  • •currently dieting to lose weight currently engaged in structured exercise using dietary weight loss supplements Resting Metabolic Rate not within 10% of predicted value

研究组 & 干预措施

Control

No Intervention

No intervention

Diet Only

Experimental

Subjects were given calorie and macronutrient intake goals and were told to hit those goals as closely as possible on a daily basis for 16 weeks.

干预措施: Diet Only (Behavioral)

Training Only

Experimental

Subjects were given a 3 times per week supervised resistance training program for 16 weeks

干预措施: Training Only (Behavioral)

Diet plus Training

Experimental

Subjects were given calorie and macronutrient intake goals and were told to hit those goals as closely as possible on a daily basis for 16 weeks. Subjects were given a 3 times per week supervised resistance training program for 16 weeks

干预措施: Diet plus Training (Behavioral)

结局指标

主要结局

Change in Fat Free Mass

时间窗: 0 and 16 weeks

Fat Free Mass as measured from DXA and recorded in Kg

Change in Fat Mass

时间窗: 0, 4, 8, 12, 16 weeks

Fat Mass as measured from DXA and recorded in Kg

Change in Resting Metabolic Rate

时间窗: 0 and 16 weeks

Resting Metabolic Rate measured via indirect calorimetry and recorded in kcal / day

Change in Visceral Fat

时间窗: 0, 4, 8, 12, 16 weeks

Fat in the Visceral Depot measured from DXA and recorded in Kg

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Todd Miller

Prinicipal Investigator

George Washington University

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