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临床试验/NCT04156386
NCT04156386已完成不适用

The Effect of Vegan or Animal Protein Ingestion on the Recovery of Skeletal Muscle Function Following Strenuous Exercise

University of Exeter2 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2019年9月23日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
30
试验地点
2
主要终点
Change in isokinetic work (W30) performed before and every 24 h after performing 300 maximal eccentric quadriceps contractions.

研究概览

简要总结

This study will assess the effect of daily post-exercise vegan (pea) and animal (whey) protein ingestion compared to placebo over 7 days of recovery from strenuous exercise. Muscle strength and soreness will be measured daily, and mechanisms underpinning recovery will be investigated in muscle biopsies taken 3, 24 and 48 hours after exercise.

详细描述

Strenuous exercise can cause muscle soreness and reduced muscle strength. It is widely acknowledged that nutritional supplements derived from animal protein sources, including whey from milk, aids recovery when taken immediately after strenuous exercise. However, the effect of vegan protein supplements are less understood, and how they affect recovery of strength and soreness is not known. This is an important area of research due to the increasing demand for plant-based protein.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Other
盲法
Double (Participant, Investigator)

入排标准

年龄范围
18 Years 至 40 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • Recreationally active
  • 18-40 years of age

排除标准

  • Regular and structured involvement in resistance training
  • Inactive participants
  • Habitual dietary protein intake <0.8g/kg bw/day and >2.0g/kg bw/day
  • Use of nutritional supplements
  • Any diagnosed metabolic conditions (diabetes), cardiovascular disease or hypertension
  • Current musculoskeletal injury
  • Use of anti-inflammatory medicines
  • Individuals with non -removable metallic implants (including heart pacemaker, cochlea implants, medication pumps, surgical clips, plates or screws) or claustrophobia
  • Individuals with an allergy to egg, fish, wheat or soy ingredients as the product is manufactured in a facility that contains these ingredients

结局指标

主要结局

Change in isokinetic work (W30) performed before and every 24 h after performing 300 maximal eccentric quadriceps contractions.

时间窗: Once per 24 hour period for 7 days

The recovery of skeletal muscle isokinetic force production following eccentric exercise using an isokinetic dynamometer

次要结局

  • Perceived quadriceps muscle soreness(Once per 24 hour period for 7 days)
  • Muscle swelling(Once per 24 hour period for 3 days)
  • Rate of protein incorporation into the muscle(Once per 24 hour period for 3 days)
  • Plasma creatine kinase (CK) activity before and every 24 h after performing 300 maximal eccentric quadriceps contractions.(Once per 24 hour period for 7 days)
  • Change in flow mediated dilation(Once hourly post exercise for 3 hours)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (2)

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