Eating Disorders Genetics Initiative (EDGI)
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 17,991
- 试验地点
- 3
- 主要终点
- Number of Participants Identified with an Eating Disorder Diagnosis by Category
研究概览
简要总结
The overarching intention of the Eating Disorder Genetics Initiative (EDGI) is to lay the foundation for all future genomic discovery in eating disorders--anorexia nervosa (AN), bulimia nervosa (BN), and binge-eating disorder (BED)--by exploring both genetic and behavioral factors. To do this, information will be collected from 4000 people who have provided DNA samples for the Anorexia Nervosa Genetics Initiative (ANGI) and the same information and DNA will be collected from an additional 16,000 people. The goal is to better understand eating disorders and how they relate to each other so that better treatments can be developed.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 15 Years 至 99 Years（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •A lifetime history of anorexia nervosa, bulimia nervosa, binge-eating disorder, or no history of any disordered eating behavior
- •Age 15-99 years
排除标准
- •History of subthreshold disordered eating behaviors
结局指标
主要结局
Number of Participants Identified with an Eating Disorder Diagnosis by Category
时间窗: Baseline
The ED100K is a web-based diagnostic questionnaire, based on the Structured Clinical Interview for Axis 1 Disorders, that applies algorithms to participant responses. The number of participants with each diagnosis (AN, BN, BED, and control) will be reported.
Age of eating disorder onset
时间窗: Baseline
Age of eating disorder onset will be considered as the age of first eating disorder symptom as self-reported in the ED100K questionnaire (ED100K). Age of onset will be reported for each eating disorder group.
次要结局
- Current eating disorder self-report total sum scores(Baseline)
- Eating disorder-related quality of life scores(Baseline)
- Health-related quality of life scores(Baseline)
- Prevalence of life-time history of major depression(Baseline)
- Prevalence of generalized anxiety disorder(Baseline)
- Current depressive symptoms sum score(Baseline)
- Current anxiety symptoms sum scores(Baseline)