Therapeutic Effect of Ultrasound Beams as an Adjunct to Reperfusion Therapy in STEMI
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 100
- 试验地点
- 2
- 主要终点
- Increase in left ventricular function
研究概览
简要总结
Successfully perfused STEMI patients will receive routine transthoracic echocardiography qid for 4 days or placebo. Myocardial function and infarct size will be evaluated at 3 and 6 months.
详细描述
Patients who had acute STEMI and successfully reperfused by either thrombolytic therapy or primary angioplasty and stenting will be included this study.
A basal routine echocardiography will be obtained in all patients after reperfusion therapy. Thereafter, patients will be divided into two groups: 1.Treatment group will receive transthoracic echocardiography using Philips HD11 XE ® for 30 minutes qid for 4 days. 2. Placebo group will have the same Philips HD11 XE ® echo transducer applied for the same time and duration on their chest but with the ultrasound turned-off. Detailed left and right ventricle function as well as performance index and stress-strain imaging will be obtained and analyzed at 3 and 6 months.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients presenting within 12 hours of their first ST- elevation myocardial infarction that is successfully reperfused; and completed baseline echocardiographic evaluation and accepted participation in the study
排除标准
- •With prior ST- elevation myocardial infarction
- •Patients presenting >12hrs
- •Not successfully reperfused
- •Not completed baseline ECHO evaluation,
- •Not accepting participation in the study
结局指标
主要结局
Increase in left ventricular function
时间窗: At 3 and 6 months
Ultrasound beams during echocardiography application expected to ameliorate the left ventricle function
次要结局
- Decrease in infarct size(At 3 and 6 months)
研究者
Ramazan Akdemir
Prof. Ramazan Akdemir, MD
Sakarya University