Ultrasonographic Assessment of Diaphragmatic Function in Obstructive Sleep Apnea Patients
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Ultrasonographic Assessment of Diaphragmatic Function in Obstructive Sleep Apnea Patients
研究概览
简要总结
Obstructive sleep apnea (OSA) is associated with altered respiratory mechanics, including diaphragmatic function. Ultrasonography provides a non-invasive tool to assess diaphragmatic structure and performance, which may correlate with OSA severity.
详细描述
Obstructive sleep apnea (OSA) is associated with altered respiratory mechanics, including diaphragmatic function. Ultrasonography provides a non-invasive tool to assess diaphragmatic structure and performance, which may correlate with OSA severity. The aim of the study is to evaluate diaphragmatic function in OSA patients using ultrasonography and to investigate its relationship with OSA severity and sleep-related parameters.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients visiting the Sleep Disordered Breathing (SDB) Unit at the Chest Medicine Department and diagnosed with obstructive sleep apnea (OSA) were included if they met the following criteria:
- •Age 18-65 years.
- •Willingness to participate in the study.
排除标准
- •Patients were excluded if they had any of the following conditions:
- •Refusal to participate in the study
- •Age <18 or >65 years
- •Systemic organ failure, including heart failure, stroke, renal failure, or liver failure; Uncontrolled diabetes mellitus
- •Diagnosed obesity hypoventilation syndrome (OHS) or other sleep disorders apart from OSA
- •Chronic respiratory diseases such as COPD, bronchial asthma, or restrictive lung disease
- •OSA patients already receiving therapy (CPAP, oral appliances, or upper airway surgery)
- •Neuromuscular disorders or other conditions affecting diaphragmatic function (malnutrition, chest trauma, or immobility)
- •Use of steroids or uncontrolled autoimmune diseases.
研究组 & 干预措施
newly diagnosed OSA patients (AHI ≥5)
30 newly diagnosed OSA patients (AHI ≥5). All participants underwent pulmonary function testing, and completed Epworth Sleepiness Scale (ESS), Berlin, and STOP-Bang questionnaires. Overnight, attended polysomnography (PSG) was performed following AASM guidelines. Diaphragm ultrasonography measured excursion, thickness at end-expiration and inspiration, and diaphragm thickening fraction (DTF).
non-OSA controls (AHI <5)
All participants underwent pulmonary function testing, and completed Epworth Sleepiness Scale (ESS), Berlin, and STOP-Bang questionnaires. Overnight, attended polysomnography (PSG) was performed following AASM guidelines. Diaphragm ultrasonography measured excursion, thickness at end-expiration and inspiration, and diaphragm thickening fraction (DTF).
结局指标
主要结局
Ultrasonographic Assessment of Diaphragmatic Function in Obstructive Sleep Apnea Patients
时间窗: 6 months
All participants underwent diaphragm thickening fraction (DTF) as a percentage (%)
次要结局
未报告次要终点
研究者
MohamedAbdElmoniem
Lecturer of chest medicine
Mansoura University