Comparative Effects of Intermittent Fasting Versus Mediterranean Diet on Obesity Management: A Randomized Controlled Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 120
- 试验地点
- 1
- 主要终点
- Body weight (kg)
研究概览
简要总结
Purpose: This study aimed to evaluate and compare the effects of intermittent fasting (IF) and the Mediterranean diet (MD) on weight loss in obese adults.
Methods: A total of 120 adults diagnosed with obesity were enrolled. Baseline data on physical activity and dietary intake were collected through structured interviews. Participants were randomly assigned to two groups for a 4-week intervention. The IF group followed a time-restricted eating schedule (16:8), while the MD group followed a structured plan of three main meals and three snacks daily. Both diets included a 500-calorie daily reduction from estimated energy needs. Anthropometric measurements were recorded at baseline and week 4.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 20 Years 至 55 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •BMI ≥ 30 kg/m²
- •absence of chronic diseases
- •no regular use of medications
- •non smokers
- •non alcohol users
- •not pregnant or breastfeeding
- •no history of bariatric surgery
- •no significant weight fluctuations (±5 kg) in the past 6 months
- •no pregnancy plans during the study period
排除标准
- •BMI < 30 kg/m²
- •Presence of any diagnosed chronic disease (e.g., diabetes, cardiovascular disease, thyroid disorders, renal or hepatic disease)
- •Regular use of medications that could affect metabolism, appetite, or body weight
- •Smoking or alcohol consumption
- •Pregnancy or breastfeeding during the study period
- •History of bariatric or other weight-related surgical procedures
- •Significant weight changes (gain or loss ≥5 kg) within the past 6 months
- •Planning pregnancy during the study period
- •Inability or unwillingness to comply with dietary intervention and follow-up requirements
研究组 & 干预措施
intermittent fasting diet intervention group
4 week time restricted intermittent fasting diet protocol
干预措施: Intermittent Fasting Diet (Other)
Mediterranean diet intervention group
4 week mediterranean diet protocol
干预措施: Mediterranean Diet (Other)
结局指标
主要结局
Body weight (kg)
时间窗: Baseline and Week 4
Body weight is measured with using the TANITA BC-418 body composition analyzer. Participants are weighed barefoot, in light clothing, and measurements are recorded in kilograms.
次要结局
- Body Mass Index (kg/m²)(Baseline and Week 4)
研究者
Kamil Dağcılar
Assistant Professor
European University of Lefke