NCT00092716已完成3 期
A Multicenter, Double-Blind, Randomized, Parallel Group, 28-Week Study to Evaluate the Efficacy and Safety of Ezetimibe and Simvastatin Co-administration Versus Atorvastatin in Patients With Hypercholesteremia
适应症
相关药物
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 入组人数
- 655
- 主要终点
- To evaluate the effect on the reduction in low density lipoprotein cholesterol (LDL-C) after the initial 6-week treatment period.
研究概览
简要总结
The purpose of this study is to determine whether an investigational medication will be more effective than an approved medication in reducing cholesterol levels.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double
入排标准
- 年龄范围
- 18 Years 至 79 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Elevated cholesterol levels
排除标准
- •Liver disease
- •Unstable medical conditions
结局指标
主要结局
To evaluate the effect on the reduction in low density lipoprotein cholesterol (LDL-C) after the initial 6-week treatment period.
次要结局
- Assess safety/tolerability and evaluate effect on HDL-C & on reduction of LDL-C
- Evaluate % of pts who attain their NCEP-ATP III goal for LDL-C @ each dose level
研究者
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